Phase 1 Coronary Clinical Trials
12 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–12 of 12 trials
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Pharmacokinetics of Regadenoson in Pediatric Patients
Myocardial IschemiaCoronary Artery Disease
GE Healthcare54 enrolled5 locationsNCT04604782
Recruiting
Phase 1
A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart Disease
stable coronary artery diseaseHealthy Volunteers
Hoffmann-La Roche196 enrolled1 locationNCT07495813
Recruiting
Phase 1
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
Premature Coronary Heart DiseaseHeterozygous Familial Hypercholesterolemia
Verve Therapeutics, Inc.85 enrolled22 locationsNCT06164730
Recruiting
Phase 1Phase 2
A Study on Yiyang Huoluo Decoction in the Treatment of Coronary Heart Disease
Coronary Heart DiseaseCoronary Artery DiseaseAtheroscleroses
Xia Liang30 enrolled1 locationNCT07493603
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart Failure
Chronic Heart FailureCoronary Artery Bypass Grafting (CABG)Chronic Ischemic Cardiomyopathy
Tasly Pharmaceutical Group Co., Ltd51 enrolled4 locationsNCT07265349
Recruiting
Phase 1
Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)
Coronary microvascular diseaseCoronary Microvascular Dysfunction (CMD)Angina Patients With Non-obstructive Coronary Artery Disease
University of Virginia150 enrolled1 locationNCT06600178
Completed
Phase 1
Assessing the pharmacokinetics, safety, and tolerability of CSL112 in healthy Japanese and Caucasian adults
Acute Coronary Syndrome
CSL Limited52 enrolled1 locationACTRN12618000805279
Completed
Phase 1
A Dose-Escalation Safety Study of Yindan Softgels in Healthy Subjects
ischemic stroke sequelaeunstable angina pectoris of coronary heart disease (CHD)
Axeon Research (Au) Pty Ltd.40 enrolled1 locationACTRN12618000582257
Completed
Phase 1
Drug-Eluting Stent Study Evaluating a New Technology in Patients with Symptomatic Ischemic Heart Disease due to Coronary Artery Blockage
Symptomatic Ischemic Heart DiseaseCoronary Artery Disease
Svelte Medical Systems, Inc.30 enrolled3 locationsACTRN12611001131943
Completed
Phase 1
To determine whether a pharmacokinetic drug-drug interaction occurs between atorvastatin and elinogrel.
chronic coronary heart disease (CHD)
Novartis Pharmaceutical Pty Limited28 enrolled1 locationACTRN12611000315910
Recruiting
Phase 1
Weight Management Program for People with Cardiac Disease and Diabetes
weight management in people with existing coronary heart disease and/or type 2 diabetes mellitus
University of Technology, Sydney168 enrolled1 locationACTRN12609000488202
Not Yet Recruiting
Phase 1
Selenium, CAD, inflammation and endothelial function
Coronary artery stenosis
University of Otago150 enrolled1 locationACTRN12606000197538