Phase 4 Coronary Clinical Trials

86 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 86 trials

Recruiting
Phase 4

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Percutaneous Coronary InterventionPeripheral Endovascular Intervention
Duke University6,000 enrolled115 locationsNCT06909565
Recruiting
Phase 4

Rivaroxaban for Children Aged Over 2 Years With Giant Coronary Artery Aneurysms After Kawasaki Disease

Kawasaki DiseaseCoronary Artery Aneurysm
Children's Hospital of Fudan University100 enrolled1 locationNCT05643651
Recruiting
Phase 4

Precision Colchicine Intervention to Suppress Atherosclerosis in TET2 Clonal Hematopoiesis

Clonal Hematopoiesis of Indeterminate PotentialColchicineCoronary Atherosclerosis Management
Shenyang Northern Hospital120 enrolled1 locationNCT07362966
Recruiting
Phase 4

Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic Therapy

Acute Coronary SyndromeMyocardial InfarctionCoronary Artery Disease+1 more
Duk-Woo Park, MD3,320 enrolled45 locationsNCT04416581
Recruiting
Phase 4

Tailored Versus Coventional AntiPlaTelet Strategy Intended After OPTIMIZEd Drug Eluting Stent

Coronary Artery Disease
Asan Medical Center3,944 enrolled33 locationsNCT05418556
Recruiting
Phase 4

Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and Non-valvular AF Undergoing PCI

Atrial FibrillationAcute Coronary SyndromeAntithrombotic Therapy+1 more
Medical University of Gdansk1,194 enrolled1 locationNCT04695106
Recruiting
Phase 4

CAPRA-EVO: a Randomized Serial PCCT Trial of Early Evolocumab After ACS

Coronary Artery DiseaseCoronary
West China Hospital233 enrolled1 locationNCT07612774
Recruiting
Phase 4

Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology (DELAY-HF), Pilot Study

Heart FailureHeart Failure Due to Coronary Artery DiseaseValvular Cardiomyopathy
Kyungsub Song80 enrolled4 locationsNCT07572032
Recruiting
Phase 4

SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue in Diabetes

AtherosclerosisType 2 Diabetes Mellitus (T2DM)Coronary Artery Disease
Junjie Yang144 enrolled2 locationsNCT07614230
Recruiting
Phase 4

Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching in Patients Undergoing PCI: The Switching Antiplatelet-8 (SWAP-8) Study

Coronary Artery Disease
University of Florida78 enrolled1 locationNCT06821191
Recruiting
Phase 4

Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation

Atrial Fibrillation (AF)Percutaneous Coronary Intervention (PCI)Oral Anticoagulation+1 more
Insel Gruppe AG, University Hospital Bern3,010 enrolled15 locationsNCT05955365
Recruiting
Phase 4

Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine

Coronary Artery Disease
Massachusetts General Hospital200 enrolled1 locationNCT05850091
Recruiting
Phase 4

The Bridging Antiplatelet Therapy With Cangrelor 2 Study

Coronary Arterial Disease (CAD)
University of Florida50 enrolled1 locationNCT07225842
Recruiting
Phase 4

Effect of ZaStaprazan on Platelet Reactivity of Clopidogrel After PercuTaneous CoronAry InteRvention

Chronic Coronary Syndrome
Yonsei University100 enrolled1 locationNCT07471867
Recruiting
Phase 4

The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

Coronary Artery Disease
VA Office of Research and Development700 enrolled9 locationsNCT05618353
Recruiting
Phase 4

Adenosine Pre-Medication in Primary Percutaneous Coronary Intervention

Acute Myocardial InfarctionST-segment elevation myocardial infarction (STEMI)No-Reflow Phenomenon+1 more
National Institute of Cardiovascular Diseases, Pakistan1,148 enrolled2 locationsNCT07536802
Recruiting
Phase 4

Multicenter Trial of Antithrombotic Strategies in Acute Coronary Syndrome With Coronary Artery Ectasia

Coronary Artery EctasiaSTEMI - ST Elevation Myocardial InfarctionNSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI)+1 more
Instituto Nacional de Cardiologia Ignacio Chavez326 enrolled1 locationNCT07511257
Recruiting
Phase 4

Effect of Intravenous Iron on Quality of Life in Older Patients With Acute Coronary Syndrome

Elderly (People Aged 65 or More)Iron Deficienciesacute coronary syndromes (ACS)
Fundación para la Investigación del Hospital Clínico de Valencia538 enrolled9 locationsNCT07476859
Recruiting
Phase 4

IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly Patients With Acute Coronary Syndrome

Coronary Artery DiseaseAntiplatelet Drugs
Shanghai Zhongshan Hospital2,846 enrolled1 locationNCT06451198
Recruiting
Phase 4

Intrapleural Ropivacaine Infusion in Cardiac Surgery

Coronary Artery DiseaseCardiac SurgeryValvular Diseases
Saint Petersburg State University, Russia116 enrolled2 locationsNCT07116343