Phase 1 Crohn's Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1Phase 2
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab
Crohn's Disease
National Institute of Allergy and Infectious Diseases (NIAID)35 enrolled1 locationNCT03167437
Recruiting
Phase 1Phase 2
Autologous Stem Cell Transplantation for Crohn's Disease
Crohn's Disease
Paul Szabolcs20 enrolled2 locationsNCT00692939
Recruiting
Phase 1
Safety of Allogeneic Human Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) to Treat Perianal Fistulas w/ Crohn's Disease
Perianal Fistula Due to Crohn's DiseaseFistula in Ano
CryoCord Sdn Bhd5 enrolled1 locationNCT05039411
Recruiting
Phase 1Phase 2
Beta-Hydroxybutyrate Feasibility Treating IBD
Inflammatory Bowel DiseasesCrohn's Disease
University of Texas at Austin20 enrolled1 locationNCT06351124
Recruiting
Phase 1
Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula
Crohn's DiseaseAnal FistulaComplex Perianal Fistulas
Jiangsu Topcel-KH Pharmaceutical Co., Ltd.8 enrolled1 locationNCT06429241
Withdrawn
Phase 1
Comparative bioavailability assessment between 2 x 10 mg R-178 tablets and 2 x 10 mg 2-amino-1,7-dihydro-6H-purine-6-thione tablets administered orally in healthy participants under fasting conditions.
2-amino-1,7-dihydro-6H-purine-6-thione is indicated for the maintenance treatment of inflammatory bowel disease (Crohn's disease or ulcerative colitis).
Zenith Technology Corporation Limited14 enrolled1 locationACTRN12622000579796
Not Yet Recruiting
Phase 1
Testosterone to treat men with mild to moderate Crohn's disease
Crohn's DiseaseHypogonadal
Fiona Stanley Hospital46 enrolled2 locationsACTRN12620000338965
Recruiting
Phase 1
A Randomized, Placebo-Controlled, Sequential Single and Multiple Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral BT-11 in Healthy Adult Male and Female Volunteers
Crohn's DiseaseInflammatory Bowel Disease
Landos Biopharma Australia Pty Ltd70 enrolled1 locationACTRN12618001210268
Completed
Phase 1
A study to primarily determine how safe and tolerable the study treatment, PTG-200 is in comparison to a matching placebo, when taken by healthy participants as a single dose or multiple dose treatment.
Crohn's Disease
Protagonist Therapeutics80 enrolled1 locationACTRN12617001426370