Phase 3 CTS Clinical Trials

22 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 22 trials

Recruiting
Phase 3

Phase 3 Pivotal Trial Comparing CARTISTEM® and Surgical Comparator for Knee Cartilage Lesions and Osteoarthritis

Knee Cartilage Defects
Medipost, Inc.300 enrolled20 locationsNCT07339111
Recruiting
Phase 3

A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU)

Molecular Mechanisms of Pharmacological ActionPeripheral Nervous System AgentsNeurotransmitter Agents+7 more
Merz Aesthetics GmbH300 enrolled26 locationsNCT07210463
Recruiting
Phase 2Phase 3

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

Radiotherapy Side EffectNeoadjuvant TherapyChemotherapy+8 more
National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos400 enrolled1 locationNCT06758830
Recruiting
Phase 3

Nebulized Ketamine for the Treatment of Major Depressive Disorder

MidazolamDepressive SymptomSevere Depression+14 more
Theresa Jacob, PhD, MPH40 enrolled1 locationNCT06752759
Recruiting
Phase 3

A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in the United States

Molecular Mechanisms of Pharmacological ActionPeripheral Nervous System AgentsNeurotransmitter Agents+7 more
Merz North America, Inc.300 enrolled28 locationsNCT07122193
Recruiting
Phase 3

Evaluate the Use of [18F]-APN-1607 PET in Subjects With AD-related Cognitive Impairment and Subjects With Normal Cognitive Function

Subjects With Mild Cognitive Impairment (MCI) of AD, Alzheimer's Disease (AD) Dementia
JYAMS PET Research & Development Limited316 enrolled2 locationsNCT07422857
Recruiting
Phase 3

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of HRS9531 Injection in Subjects With Obstructive Sleep Apnea (OSA) and Obesity Who Are on Positive Airway Pressure Ventilation (PAP) Therapy

Subjects With Moderate-to-severe OSA and Obesity Who Are on PAP Therapy
Fujian Shengdi Pharmaceutical Co., Ltd.140 enrolled1 locationNCT06994650
Recruiting
Phase 3

The Study of Efficacy and Safety of Dimephosphon® in Acute Ischemic Stroke

StrokeCerebrovascular DisordersAcute Stroke+2 more
Tatchempharmpreparaty, JSC184 enrolled6 locationsNCT07167550
Recruiting
Phase 3

NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer)

Neoadjuvant ChemotherapyResectable Pancreatic CancerEffects of Chemotherapy
Seoul National University Hospital609 enrolled2 locationsNCT05529940
Recruiting
Phase 3

Clobetasol Propionate Ophthalmic Nanoemulsion, 0.05% in the Treatment of Inflammation After Cataract Surgery in Pediatric Population

Cataracts Infantile
Salvat60 enrolled1 locationNCT05724446
Completed
Phase 2Phase 3

Effect of purple Plum juice on blood pressure in overweight/obese participants.

mild hypertension in overweight/obese subjects.
A/Prof Michael Mathai70 enrolled1 locationACTRN12614001270606
Recruiting
Phase 2Phase 3

Comparison of 0.8% sevoflurane versus Entonox for labour analgesia

Active Labour in healthy parturientsPost analgesic nausea and vomitingShort term memory and amnesic effects of sevoflurane and entonox
University of Malaya46 enrolled1 locationACTRN12614000805673
Recruiting
Phase 3

Phase 3 Accelerated BEP Trial: A randomised phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours

Intermediate and poor-risk metastatic germ cell tumours (GCTs)
University of Sydney500 enrolled22 locationsACTRN12613000496718
Completed
Phase 3

Mepitel Film for the prevention of skin ulceration caused by radiation therapy in breast cancer patients.

Acute side effects of radiation therapy for breast cancerBreast cancer patients treated with radiation
University of Otago80 enrolled1 locationACTRN12612000949886
Completed
Phase 3

Effect of warmed bupivacaine on the efficacy of ultrasound guided axillary brachial plexus block

need of adjuncts to local anesthetics in regional anesthesia
Tunisian Military Hospital80 enrolled1 locationACTRN12612000923864
Recruiting
Phase 3

Intrauterine Lidocaine versus Placebo in Conjunction with Paracervical Block for Pain Relief During Fractional Curettage: A Randomized Controlled Trial

Pain score in women with abnormal uterine bleeding who undergoing fractional and curettageAdverse effects in women with abnormal uterine bleeding who undergoing fractional and curettageAdditional drug requirement in women with abnormal uterine bleeding who undergoing fractional and curettage
Khon Kaen Hospital230 enrolled1 locationACTRN12611000449932
Terminated
Phase 3

Tamoxifen and Exemestane Trial Bone Substudy - A substudy to Amendment 2 of the IBCSG 25-02 / BIG 3-02: Tamoxifen and Exemestane Trial (ACTRN12605000418673) hereby referred to as TEXT-2, which evaluates the effects of exemestane plus Gonadotropin-releasing hormone (GnRH) analogue as adjuvant therapy for premenopausal women with endocrine responsive breast cancer

Effects of adjuvant endocrine therapies on bone mineral density in pre-menopausal breast cancer patients.
Breast Cancer Trials200 enrolled1 locationACTRN12609000532202
Completed
Phase 2Phase 3

The use of tiagabine and gabapentin in the treatment of social anxiety disorder in 8 patients

Subjects with social anxiety disorder
Maria Urbano, M.D.8 enrolled1 locationACTRN12609000091202
Completed
Phase 3

A study comparing the efficacy and safety of once-daily oral rivaroxaban with warfarin for the prevention of stroke and embolism in patients with atrial fibrillation.

StrokeNon-central nervous system systemic embolism in subjects with non-valvular atrial fibrillation.
Bayer Australia Limited14,269 enrolled1 locationACTRN12607000214437
Recruiting
Phase 3

Cancer vaccine study for unresectable stage III non-small cell lung cancer

Non-small cell lung cancer (NSCLC) subjects with unresectable stage III disease
Merck KGaA, Darmstadt, Germany1,322 enrolled1 locationACTRN12607000173493