Dental Restoration Clinical Trials

11 recruitingLast updated: May 13, 2026

There are 11 actively recruiting dental restoration clinical trials across 7 countries. Studies span Not Applicable. Top locations include Al Mansurah, Dakahliya, Egypt, Leuven, Belgium, Basel, Canton of Basel-City, Switzerland. Updated daily from ClinicalTrials.gov.


Dental Restoration Trials at a Glance

11 actively recruiting trials for dental restoration are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Al Mansurah, Leuven, and Basel. Lead sponsors running dental restoration studies include Mansoura University, Cukurova University, and Cairo University.

Browse dental restoration trials by phase

Treatments under study

About Dental Restoration Clinical Trials

Looking for clinical trials for Dental Restoration? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Dental Restoration trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Dental Restoration clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting

Clinical Investigation Measuring the Long Term Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.

Dental Restoration, PermanentEndodontic TreatmentDental Restorations
Septodont275 enrolled8 locationsNCT06955429
Recruiting
Not Applicable

Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM

Dental CariesDental Restoration, PermanentTooth Diseases
Cukurova University12 enrolled1 locationNCT07031856
Recruiting
Not Applicable

3M(TM) Filtek(TM) Supreme Flowable Composites for Class IV and Veneers

Dental RestorationDental Veneers
New York University75 enrolled1 locationNCT07128589
Recruiting

Colour Match, Stability, and Patient's Satisfaction of Single-Shade Composites in Anterior Teeth

Tooth InjuriesDental Restoration, Permanent
Mahidol University23 enrolled1 locationNCT07309653
Recruiting
Not Applicable

Clinical Performance of Full Coverage Hybrid Ceramic Crowns in the Aesthetic Zone: A Randomized Clinical Trial

Dental Restoration Failure of Marginal IntegrityPoor Aesthetic of Existing Restoration of Tooth
Karim Ahmed Awadallah Osman54 enrolled1 locationNCT07264491
Recruiting
Not Applicable

Effect of Phosphoric Acid Etching Duration on Direct Resin-Based Composite Restorations in Permanent Anterior Teeth

Dental Restoration, PermanentDental Caries (Disorder)Dental Restoration Failure
Florin Eggmann66 enrolled1 locationNCT06991842
Recruiting
Not Applicable

Clinical Evaluation of Short Dentin Etching

Dental Restoration Failure of Marginal IntegrityHypersensitivity Dentin
Mansoura University30 enrolled1 locationNCT06772051
Recruiting
Not Applicable

One-year Clinical Evaluation of Bulk-fill Versus Conventional Incremental Posterior Restoration by FDI Criteria

Post Dental Restoration
Cairo University69 enrolled1 locationNCT02891967
Recruiting
Not Applicable

Resin Modified Glass Ionomer Versus Self-Adhesive Resin Composite Restorative Systems

Secondary Caries Dental Restoration Failure of Marginal Integrity
Mansoura University35 enrolled1 locationNCT06543680
Recruiting
Not Applicable

Comparative Clinical Evaluation of BioFlx, Zirconia, and Stainless-Steel Crowns in Primary Molars

Dental Restoration
Mansoura University51 enrolled1 locationNCT06450093
Recruiting

Validation of the O-bridge Protocol: a Prospective, Multicenter Trial

Quality of LifeMandibular ReconstructionBenign or Malignant Tumour of the Oral Cavity+2 more
AZ Sint-Jan AV80 enrolled5 locationsNCT04007783