Phase 1 Dependence Clinical Trials
8 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–8 of 8 trials
Recruiting
Phase 1
Oral Cannabidiol for Tobacco Cessation
Tobacco Use DisorderTobacco DependenceTobacco Use Cessation+2 more
Johns Hopkins University50 enrolled1 locationNCT05445804
Recruiting
Phase 1
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
Nicotine DependenceNicotine Vaping
University of California, San Francisco18 enrolled1 locationNCT05962229
Recruiting
Phase 1
Safety Study of a Disrupted Adenovirus (Ad) Serotype Cocaine Vaccine for Cocaine-dependent Individuals
Cocaine Dependence
Weill Medical College of Cornell University150 enrolled1 locationNCT02455479
Recruiting
Phase 1
A Clinical Trial to Assess Pharmacokinetic Profiles, Safety and Tolerability of IVL3004 and IVL4002 in Healthy Male Subjects.
Multiple SclerosisOpioid DependenceAlcohol Dependence
Inventage Lab., Inc.40 enrolled1 locationNCT05620940
Recruiting
Phase 1
Effects of Cannabidiol on Stress and Nicotine Withdrawal
StressNicotine DependenceTobacco Smoking+1 more
Johns Hopkins University90 enrolled1 locationNCT07001930
Recruiting
Phase 1Phase 2
Overcoming Nicotine Dependence to Enable Quitting
Smoking CessationSmoking BehaviorsNicotine Dependence+2 more
Rush University Medical Center780 enrolled1 locationNCT05513872
Recruiting
Phase 1
Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia
Tobacco DependenceNicotine Dependence
University of Southern California800 enrolled2 locationsNCT05487807
Active
Phase 1
A pilot study of the potential acceptability of vaporised nicotine products for smoking cessation or long-term substitution among smokers
Tobacco Dependence
The University of Queensland15 enrolled1 locationACTRN12615000829516