Dependence Clinical Trials

1 recruiting

Dependence Trials at a Glance

110 actively recruiting trials for dependence are listed on ClinicalTrialsFinder across 6 cities in 25 countries. The largest study group is Not Applicable with 49 trials, with the heaviest enrollment activity in Baltimore, Toronto, and Houston. Lead sponsors running dependence studies include University of California, San Francisco, Yale University, and Johns Hopkins University.

Browse dependence trials by phase

Treatments under study

About Dependence Clinical Trials

Looking for clinical trials for Dependence? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Dependence trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Dependence clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 110 trials

Recruiting

Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

AlcoholismAlcohol DrinkingAlcohol Dependence+2 more
National Institute on Alcohol Abuse and Alcoholism (NIAAA)1,000 enrolled1 locationNCT02108080
Recruiting
Early Phase 1

Smart Olfaction App to Reduce Relapse

Nicotine Dependence
University of Houston132 enrolled1 locationNCT07007195
Recruiting
Not Applicable

Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging

Drug AbuseNicotine Dependence
National Institute on Drug Abuse (NIDA)1,000 enrolled1 locationNCT01036581
Recruiting
Phase 4

Beta-Adrenergic Modulation of Drug Cue Reactivity

Tobacco Use DisorderNicotine DependenceCigarette Smoking
University of Oklahoma80 enrolled1 locationNCT05587361
Recruiting
Phase 2

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Chronic PainDrug Dependence of Morphine TypeSymptom, Withdrawal
University of Calgary40 enrolled1 locationNCT04939623
Recruiting

Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees

AnxietyPsychological StressHealth Behavior+12 more
Jacobs University Bremen gGmbH363 enrolled2 locationsNCT06899308
Recruiting
Not Applicable

Reducing Opioid Use for Chronic Pain Patients Following Surgery

Opioid UsePostoperative PainChronic Pain+1 more
University Health Network, Toronto210 enrolled1 locationNCT03675386
Recruiting

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Healthy ControlSchizophreniaPost Traumatic Stress Disorder+4 more
Yale University100 enrolled1 locationNCT01730781
Recruiting
Not Applicable

Social Media Support Groups for Adolescent Vaping Cessation

VapingNicotine DependenceVaping Cessation
University of California, San Francisco60 enrolled1 locationNCT07540780
Recruiting
Not Applicable

Transcranial Magnetic Stimulation (TMS) Effects Using Magnetoencephalography (MEG) Study

Alcohol Use DisorderAlcohol ConsumptionAlcohol Dependence
Wake Forest University Health Sciences10 enrolled1 locationNCT06770556
Recruiting
Not Applicable

Orexin s Role in the Neurobiology of Substance Use Disorder

Nicotine Dependence
National Institute on Drug Abuse (NIDA)140 enrolled1 locationNCT05630781
Recruiting
Not Applicable

Feasibility of Integrating Olfactory Stimuli Into Virtual Reality Cue Exposure for Patients With Alcohol Dependence

Alcohol Dependence
Charite University, Berlin, Germany20 enrolled1 locationNCT07388693
Recruiting
Phase 2

Cannabidiol for Reducing Cigarette Use

Tobacco Use DisorderTobacco DependenceTobacco Smoking
University of California, Los Angeles120 enrolled1 locationNCT06218056
Recruiting
Not Applicable

Auricular Stimulation for Nicotine Withdrawal in Psychiatric Inpatients

AnxietyTobacco Use DisorderNicotine Dependence+2 more
Chiao-Chiao Liao60 enrolled1 locationNCT07466875
Recruiting
Early Phase 1

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

Nicotine Dependence, CigarettesAdverse Childhood Experiences
Duke University150 enrolled1 locationNCT05665465
Recruiting
Not Applicable

Neuroimaging of Adolescent Cannabis Use Treatment

Cannabis UseCannabis SmokingCannabis Use Disorder+3 more
Indiana University80 enrolled1 locationNCT07340554
Recruiting
Not Applicable

Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use Disorder (AUD)

AlcoholismAlcohol Use DisorderAlcohol Dependence+3 more
Brainsway186 enrolled9 locationsNCT07216872
Recruiting
Not Applicable

Neuromodulation and Mindfulness Patients With AUD

Alcohol Dependence
Charite University, Berlin, Germany140 enrolled1 locationNCT06308484
Recruiting
Not Applicable

Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction

SmokingSmoking BehaviorsNicotine Dependence
Yale University256 enrolled1 locationNCT06077240
Recruiting
Phase 4

Smoking Cessation and Menstrual Cycle Phase

Smoking CessationSubstance Use DisordersNicotine Dependence+2 more
Centre for Addiction and Mental Health1,200 enrolled1 locationNCT05515354