Phase 1 Dermatitis Clinical Trials

43 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 120 of 43 trials

Recruiting
Phase 1

Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic Dermatitis

Atopic DermatitisLupusHyper IgE Syndrome From STAT3 Mutation+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT07262983
Recruiting
Phase 1

FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients

Healthy ParticipantsAtopic Dermatitis
Pfizer119 enrolled5 locationsNCT06564389
Recruiting
Phase 1

A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Moderate to Severe Atopic Dermatitis (AD)

Atopic Dermatitis
Bambusa Therapeutics99 enrolled10 locationsNCT07239947
Recruiting
Phase 1

A First-in-human Study to Investigate Single Doses of DCY636 in Healthy Volunteers and Multiple Doses in Participants With Moderate to Severe Atopic Dermatitis

Dermatitis Atopic
Novartis Pharmaceuticals63 enrolled1 locationNCT07604324
Recruiting
Phase 1

A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)

Atopic Dermatitis
Bambusa Therapeutics237 enrolled14 locationsNCT06808477
Recruiting
Phase 1

Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)

Atopic Dermatitis
National Institute of Allergy and Infectious Diseases (NIAID)86 enrolled8 locationsNCT06504160
Recruiting
Phase 1

First-in-Human Trial to Assess REGN20423 in Healthy Adult Participants and Adult Participants With Atopic Dermatitis

Healthy VolunteerAtopic Dermatitis
Regeneron Pharmaceuticals144 enrolled1 locationNCT07527923
Recruiting
Phase 1Phase 2

HL-300 Ointment in Patients With Mild-to-Moderate Atopic Dermatitis

Atopic Dermatitis
Hangzhou Highlightll Pharmaceutical Co., Ltd156 enrolled1 locationNCT07629778
Recruiting
Phase 1

ZYG24002 Lotion to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy in Adult Patients With Mild to Moderate Seborrheic Dermatitis

Seborrheic Dermatitis
Sinomune Pharmaceutical Co., Ltd48 enrolled1 locationNCT07404033
Recruiting
Phase 1

Phase 1a/1b Study of TRB-061 in Healthy Participants & Patients With Atopic Dermatitis

Moderate-to-severe Atopic Dermatitis
TRex Bio, Inc.115 enrolled15 locationsNCT06934252
Recruiting
Phase 1

Study of S-4321 in Participants With an Autoimmune or Immune-mediated Disease

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Psoriasis (PsO)+3 more
Seismic Therapeutic AU Pty Ltd24 enrolled2 locationsNCT07455578
Recruiting
Phase 1

Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234

EczemaAtopic Dermatitis (AD)
Arcutis Biotherapeutics, Inc.125 enrolled1 locationNCT07453602
Recruiting
Phase 1

A Phase 1 Clinical Study Comparing GS101 and Dupixent® After Subcutaneous Injection

Atopic Dermatitis (AD)
Jiangsu Genscend Biopharmaceutical Co., Ltd294 enrolled1 locationNCT07411755
Recruiting
Phase 1

A Study of SKB575 (HBM7575) Injection in Healthy Participants and Atopic Dermatitis Participants

Atopic Dermatitis
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.90 enrolled2 locationsNCT07488065
Recruiting
Phase 1

The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis

Atopic Dermatitis (AD)
Daniel Kaplan8 enrolled2 locationsNCT06928246
Recruiting
Phase 1

A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis

Moderate-to-severe Atopic Dermatitis
Sitryx Therapeutics Ltd149 enrolled14 locationsNCT07558668
Recruiting
Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases

healthy adult participantsHealthy ParticipantsHealthy Volunteers+4 more
BeiGene211 enrolled13 locationsNCT06342713
Recruiting
Phase 1

Clinical Evaluation of Skin Microbiome an Over-The-Counter (OTC) Drug for Atopic Dermatitis

Atopic Dermatitis (AD)
Good Molecules, LLC36 enrolled1 locationNCT07146971
Recruiting
Phase 1

A Phase I Study of Single Subcutaneous Dose of SHR-1894 in Healthy Subjects

Dermatitis
Suzhou Suncadia Biopharmaceuticals Co., Ltd.40 enrolled1 locationNCT07414602
Recruiting
Phase 1

A Study to Compare the Pharmacokinetics, Pharmacodynamic, Immunogenicity, and Safety of CKD-706 With US-Dupixent®, and EU-Dupixent® in Healthy Adult Participants.

Atopic Dermatitis
Chong Kun Dang Pharmaceutical519 enrolled2 locationsNCT07358156