Phase 1 Diagnosis Clinical Trials

11 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 111 of 11 trials

Recruiting
Phase 1

Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617

Prostate CancerLocalized Prostate CarcinomaHigh-risk Prostate Cancer+2 more
Thomas Hope45 enrolled1 locationNCT07054346
Recruiting
Phase 1

Effects of High-Fiber Diet on Gut Microbiota, Metabolism, and Immune Microenvironment in Solid Tumor Patients: A Clinical Study

Colorectal Cancer (Diagnosis)Diet HabitsHigh-fibre Diet
West China Hospital25 enrolled1 locationNCT07477522
Recruiting
Phase 1

Precision Antibiotic Dosing for Appendectomy

Appendicitis (Diagnosis)
University of Michigan46 enrolled1 locationNCT06860802
Recruiting
Phase 1Phase 2

Venetoclax Plus Hypomethylating Agents and Subcutaneous Cytarabine for CEBPA-Mutated AML

Acute Myeloid Leukemia (AML)CEBPA MutationUnfit, New-diagnosis AML
The First Affiliated Hospital of Soochow University29 enrolled1 locationNCT07451912
Recruiting
Phase 1Phase 2

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

SarcomaCancerLeukaemia+2 more
Essen Biotech83 enrolled1 locationNCT07410676
Recruiting
Phase 1

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

Endometrial CancerMetastasisEndometrial Endometrioid Adenocarcinoma+5 more
UNC Lineberger Comprehensive Cancer Center58 enrolled1 locationNCT05542407
Recruiting
Phase 1Phase 2

Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)

Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaAcute Lymphoid Leukemia+4 more
University of Florida40 enrolled4 locationsNCT05322850
Recruiting
Phase 1

Robot-Assisted Prostate Biopsy With a Novel Ultrasound Probe

Prostate Cancer (Diagnosis)
Johns Hopkins University60 enrolled1 locationNCT07271017
Recruiting
Phase 1Phase 2

A Study of ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC

ImmunotherapyColorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc.66 enrolled15 locationsNCT07244705
Recruiting
Phase 1

Repeated Neural Stem Cell Based Virotherapy for Newly Diagnosed High Grade Glioma

Glioma, MalignantNew Diagnosis Tumor
Northwestern University20 enrolled1 locationNCT06169280
Withdrawn
Phase 1

A Phase 1 Single Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EARLI-001

Cancer Diagnosis
Earli Pty. Ltd.10 enrolled1 locationACTRN12622001571763