Phase 2 Diffuse Large B Cell Lymphoma Clinical Trials
33 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 33 trials
Recruiting
Phase 1Phase 2
A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies
Diffuse Large B Cell LymphomaChronic Lymphocytic LeukemiaNon-Hodgkin Lymphoma+6 more
BeOne Medicines614 enrolled127 locationsNCT05006716
Recruiting
Phase 1Phase 2
Autologous Stem Cell Transplant Followed by Polatuzumab Vedotin in Patients With B-cell Non-Hodgkin and Hodgkin Lymphoma
Diffuse Large B Cell LymphomaHodgkin LymphomaMantle Cell Lymphoma+6 more
New York Medical College20 enrolled1 locationNCT04491370
Recruiting
Phase 2
Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy
Diffuse Large B Cell Lymphoma
H. Lee Moffitt Cancer Center and Research Institute27 enrolled1 locationNCT05757219
Recruiting
Phase 2
CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based Autologous Stem Cell Transplant
Diffuse Large B Cell Lymphoma
Washington University School of Medicine36 enrolled1 locationNCT06687772
Recruiting
Phase 1Phase 2
Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)
Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaChronic Lymphocytic Leukemia+8 more
Vironexis Biotherapeutics Inc.32 enrolled9 locationsNCT06533579
Recruiting
Phase 2
CAR-T Followed by Bispecific Antibodies
DLBCL - Diffuse Large B Cell LymphomaLarge B-cell Lymphoma
Abramson Cancer Center at Penn Medicine42 enrolled2 locationsNCT04889716
Recruiting
Phase 1Phase 2
Dose Escalation and Dose Expansion Study of MDX2003 in Patients With Different Types of Lymphoma
DLBCL - Diffuse Large B Cell LymphomaLymphomaLymphoplasmacytic Lymphoma+4 more
ModeX Therapeutics, An OPKO Health Company180 enrolled1 locationNCT07249905
Recruiting
Phase 2
Selinexor in Combination With R-CHOP as the First-line Therapy for TP53-mutated DLBCL Patients (Smart Trial)
Diffuse Large B Cell Lymphoma
Sun Yat-sen University42 enrolled2 locationsNCT06517511
Recruiting
Phase 1Phase 2
Clinical Trial of TQB2825 Injection Combined Immunochemotherapy in Subjects With Diffuse Large B Cell Lymphoma
Diffuse Large B Cell Lymphoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.90 enrolled25 locationsNCT06829771
Recruiting
Phase 2
DALY II Japan/MB-CART2019.1 for DLBCL
DLBCL - Diffuse Large B Cell Lymphoma
Miltenyi Biomedicine GmbH31 enrolled5 locationsNCT07288879
Recruiting
Phase 2
A Study of Circulating Tumor DNA (ctDNA) Testing for People With B-Cell Lymphoma
Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaStage III High Grade B-Cell Lymphoma+7 more
Memorial Sloan Kettering Cancer Center50 enrolled7 locationsNCT06736613
Recruiting
Phase 2
Pirtobrutinib, Lisaftoclax, and Rituximab in the Treatment of R/R DLBCL
DLBCL - Diffuse Large B Cell Lymphoma
The First Affiliated Hospital of Soochow University29 enrolled1 locationNCT07255963
Recruiting
Phase 1Phase 2
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Endometrial CancerAdvanced Solid TumorDiffuse Large B Cell Lymphoma+5 more
Novartis Pharmaceuticals275 enrolled60 locationsNCT04104776
Recruiting
Phase 1Phase 2
Phase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell Lymphoma
Diffuse Large B Cell LymphomaLarge B-cell LymphomaPrimary Mediastinal Large B Cell Lymphoma+2 more
Pell Bio-Med Technology Co., Ltd.49 enrolled5 locationsNCT05326243
Recruiting
Phase 2
Epcoritamab-CAR T Cells for Large B-cell Lymphomas
Lymphoma, Non-HodgkinRelapsed Diffuse Large B Cell Lymphoma
Abramson Cancer Center at Penn Medicine31 enrolled1 locationNCT06458439
Recruiting
Phase 2
Chidamide Plus R-CHOP in Newly Diagnosed Double-Expressor Diffuse Large B-Cell Lymphoma With Other Molecular Subtypes
DLBCL - Diffuse Large B Cell LymphomaChidamideR-CHOP Chemotherapy+1 more
The First Affiliated Hospital with Nanjing Medical University148 enrolled1 locationNCT06891157
Recruiting
Phase 2
AZA Combined With RCHOP in P53-mutated DLBCL.
DLBCL - Diffuse Large B Cell LymphomaTP53
The First Affiliated Hospital of Xiamen University52 enrolled1 locationNCT06158399
Recruiting
Phase 2
Lenalidomide Combined With G-CHOP in the Treatment of Newly Diagnosed DLBCL With FL
DLBCL - Diffuse Large B Cell LymphomaFollicular Lymphoma
The First Affiliated Hospital of Xiamen University38 enrolled1 locationNCT06151080
Recruiting
Phase 2
Polatuzumab, Rituximab and Orelabrutinib Combination Regimen (PRO) in the Treatment of Elderly Frail Patients with Treatment-naive Non-GCB DLBCL
Diffuse Large B Cell Lymphoma
Affiliated Hospital of Nantong University30 enrolled2 locationsNCT06530511
Recruiting
Phase 2
Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell Lymphoma
Diffuse Large B Cell Lymphoma
Ruijin Hospital76 enrolled1 locationNCT05348213