Early Phase 1 Disorder Clinical Trials
52 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 52 trials
Recruiting
Early Phase 1
Clinical Study of B001 Injection in Subjects With Neuromyelitis Optic Spectrum Disorder (NMOSD)
NMO Spectrum Disorder
Shanghai Pharmaceuticals Holding Co., Ltd45 enrolled4 locationsNCT05145361
Recruiting
Early Phase 1
Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
Sleep Disorders, Circadian Rhythm
University of Virginia50 enrolled1 locationNCT05701969
Recruiting
Early Phase 1
Mental Health in Veterans and Families After Group Therapies
Post-Traumatic Stress Disorders
Soul Medicine Institute100 enrolled1 locationNCT01327690
Recruiting
Early Phase 1
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine
Major Depressive Disorder (MDD)
University of Pennsylvania10 enrolled1 locationNCT06788249
Recruiting
Early Phase 1
Pilot of Mailing Buprenorphine
Opioid-use Disorder
Medical University of South Carolina20 enrolled2 locationsNCT07421102
Recruiting
Early Phase 1
Cannabidiol in Opioid Use Disorder and Chronic Pain
Chronic PainOpioid-use Disorder
Yale University34 enrolled1 locationNCT04587791
Recruiting
Early Phase 1
Early Feasibility of the Nervonik Peripheral Nerve Stimulation Device
Peripheral Nerve Disorder
Nervonik30 enrolled1 locationNCT06772142
Recruiting
Early Phase 1
Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
Blood Pressure DisordersSalt; Excess
Wake Forest University Health Sciences120 enrolled1 locationNCT04026776
Recruiting
Early Phase 1
SV2A Density Cannabis Use Disorder
HealthyCannabis Use Disorder
Yale University51 enrolled1 locationNCT05472818
Recruiting
Early Phase 1
A Clinical Trial Comparing Buprenorphine Formulations for High Potency Synthetic Opioid Use
Opioid-use Disorder
Rachel R. Luba60 enrolled1 locationNCT06726200
Recruiting
Early Phase 1
Psilocybin for Prolonged Grief Disorder
Prolonged grief disorder
University of Virginia12 enrolled1 locationNCT06724289
Recruiting
Early Phase 1
Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design
Autism Spectrum Disorder
Penn State University50 enrolled1 locationNCT07432776
Recruiting
Early Phase 1
JIT: Effect of Pain on DT in TMD
Temporomandibular disorder (TMD)
University of Minnesota160 enrolled1 locationNCT06659991
Recruiting
Early Phase 1
Anxiety During Abstinence in AUD
Alcohol Use Disorder
Columbia University60 enrolled1 locationNCT06793488
Recruiting
Early Phase 1
Impulsivity Domains and Subjective Response
Alcohol Use Disorder
Jessica Weafer250 enrolled2 locationsNCT05929677
Recruiting
Early Phase 1
Safety Profile of Psilocybin for Cocaine Use Disorder
Cocaine Use Disorder
University of California, Los Angeles10 enrolled1 locationNCT06102434
Recruiting
Early Phase 1
Open-label Study to Evaluate Brain α-Synuclein Deposition Using PET and [18F]MK-0947 in Parkinson's Disease
Parkinson's DiseaseParkinson's Disease (PD)Parkinson's Disease (Disorder)
Invicro22 enrolled1 locationNCT07348250
Recruiting
Early Phase 1
Methamphetamine and Troriluzole
Methamphetamine Use Disorder
William Stoops40 enrolled1 locationNCT06989853
Recruiting
Early Phase 1
Suvorexant and Alcohol
Alcohol Use Disorder
William Stoops30 enrolled1 locationNCT06326684
Recruiting
Early Phase 1
Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases
Myasthenia GravisAutoimmune EncephalitisMultiple Sclerosis+2 more
Tianjin Huanhu Hospital12 enrolled1 locationNCT06939166