Early Phase 1 Disorder Clinical Trials
56 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 56 trials
Recruiting
Early Phase 1
Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction
Voice disordersMuscle Tension DysphoniaVocal Fold Polyp+1 more
Massachusetts General Hospital100 enrolled2 locationsNCT05970562
Recruiting
Early Phase 1
JIT: Effect of Pain on DT in TMD
Temporomandibular disorder (TMD)
University of Minnesota160 enrolled1 locationNCT06659991
Recruiting
Early Phase 1
[C-11]NPA PET-amphetamine in Cocaine Use Disorders
Cocaine Use Disorder
Rajesh Narendran30 enrolled1 locationNCT05011760
Recruiting
Early Phase 1
Breathing for Two: Inspiratory Muscle Strength Training for Supporting Healthy Blood Pressure in Pregnancy
PregnancyHypertension Disorders in PregnancyBlood Pressure Measurement in Pregnancy+1 more
University of Arizona80 enrolled1 locationNCT07687745
Recruiting
Early Phase 1
Imaging CRF X NOP Interactions in CUD
Cocaine Use Disorder
Rajesh Narendran80 enrolled1 locationNCT05008146
Recruiting
Early Phase 1
Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
Blood Pressure DisordersSalt; Excess
Wake Forest University Health Sciences120 enrolled1 locationNCT04026776
Recruiting
Early Phase 1
Open-label Study to Evaluate Brain α-Synuclein Deposition Using PET and [18F]MK-0947 in Parkinson's Disease
Parkinson's DiseaseParkinson's Disease (PD)Parkinson's Disease (Disorder)
Invicro22 enrolled2 locationsNCT07348250
Recruiting
Early Phase 1
Measuring Acute Drug Demand in Humans
Opioid-use DisorderOpioid Dependence
University of Maryland, Baltimore75 enrolled1 locationNCT05829655
Recruiting
Early Phase 1
Psilocybin for Prolonged Grief Disorder
Prolonged grief disorder
University of Virginia12 enrolled1 locationNCT06724289
Recruiting
Early Phase 1
REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study
Disorders of Consciousness
Samuel Snider, MD2 enrolled1 locationNCT07228286
Recruiting
Early Phase 1
Cocaine and Pentoxifylline (BED IN 47)
Cocaine Use Disorder
William Stoops30 enrolled1 locationNCT07086794
Recruiting
Early Phase 1
Methamphetamine and Troriluzole
Methamphetamine Use Disorder
William Stoops40 enrolled1 locationNCT06989853
Recruiting
Early Phase 1
Suvorexant and Alcohol
Alcohol Use Disorder
William Stoops30 enrolled1 locationNCT06326684
Recruiting
Early Phase 1
Imaging CRF X NOP Interactions in Alcohol Use Disorder
Alcohol Use Disorder
Rajesh Narendran90 enrolled1 locationNCT07612631
Recruiting
Early Phase 1
A Clinical Trial Comparing Buprenorphine Formulations for High Potency Synthetic Opioid Use
Opioid-use Disorder
Rachel R. Luba60 enrolled1 locationNCT06726200
Recruiting
Early Phase 1
Impact of rTMS on Abnormal Cortical fMRI in Patients With Dystonia
Dystonia Disorder
Northwell Health10 enrolled1 locationNCT07626216
Recruiting
Early Phase 1
Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine
Major Depressive Disorder
Emory University140 enrolled1 locationNCT05327699
Recruiting
Early Phase 1
Impulsivity Domains and Subjective Response
Alcohol Use Disorder
Jessica Weafer250 enrolled2 locationsNCT05929677
Recruiting
Early Phase 1
Clinical Study of B001 Injection in Subjects With Neuromyelitis Optic Spectrum Disorder (NMOSD)
NMO Spectrum Disorder
Shanghai Pharmaceuticals Holding Co., Ltd45 enrolled4 locationsNCT05145361
Recruiting
Early Phase 1
Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
Sleep Disorders, Circadian Rhythm
University of Virginia50 enrolled1 locationNCT05701969