RecruitingEarly Phase 1NCT07825818

Imaging Mitochondrial Complex-I in Alcohol Use Disorder

Imaging Mitochondrial Complex-I With [F-18]BCPP-EF Positron Emission Tomography (PET) in Alcohol Use Disorder (AUD)


Sponsor

Rajesh Narendran

Enrollment

100 participants

Start Date

Sep 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

Studies proposed in this application will image mitochondrial Complex-I (MCI-I) and cerebral glucose metabolism (CGM) in alcohol use disorder (AUD) and matched healthy controls


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called [F-18]BCPP-EF and a drug called [F-18]FDG for people with alcohol use disorder (aud) and healthy controls group - age and sex-matched. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG[F-18]BCPP-EF

Radiotracer to measure binding to mitochondria complex -I

DRUG[F-18]FDG

Radiotracer to measure cerebral glucose metabolism


Locations(1)

University of PIttsburgh

Pittsburgh, Pennsylvania, United States

View Full Details on ClinicalTrials.gov

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NCT07825818


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