Phase 2 dMMR Colorectal Cancer Clinical Trials

3 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 1–3 of 3 trials

Recruiting

Phase 1Phase 2

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Endometrial CancerAdvanced Solid TumorsMSI-H or dMMR Advanced Solid Tumors+4 more

Eikon Therapeutics160 enrolled10 locationsNCT07262619

Recruiting

Phase 2

Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

Colon CancerdMMR Colorectal Cancer

University of Iowa25 enrolled1 locationNCT05239546

Recruiting

Phase 2

Cadonilimab in Locally Advanced MSI-H/dMMR Colorectal Cancer

dMMR Colorectal Cancer

Cancer Institute and Hospital, Chinese Academy of Medical Sciences50 enrolled1 locationNCT05815290