Phase 2 DNA Clinical Trials
16 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–16 of 16 trials
Recruiting
Phase 2
Thinking Zinc: a Study of Zinc Supplements on the Navajo Nation
Immune System DisorderDNA Damage
University of New Mexico100 enrolled1 locationNCT03908736
Recruiting
Phase 2
A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
Colorectal, CancerMinimal Residual DiseasectDNA+3 more
M.D. Anderson Cancer Center20 enrolled1 locationNCT07136077
Recruiting
Phase 2
Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)
Breast CancerTriple-Negative Breast CancerCirculating Tumor DNA+1 more
Dana-Farber Cancer Institute40 enrolled7 locationsNCT04434040
Recruiting
Phase 2
Randomized Trial of Plasma ctDNA Methylation-Guided Adjuvant Therapy in T4N0 and Low-Risk Stage III Colorectal Cancer
Colorectal, CancerChemotherapyctDNA
Fudan University340 enrolled1 locationNCT07562503
Recruiting
Phase 2
A Randomized Controlled Trial of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy Decision-Making in High-Risk Stage III (T4N+ or T1-3N2) Colorectal Cancer
Colorectal, CancerChemotherapyctDNA
Fudan University100 enrolled1 locationNCT07562490
Recruiting
Phase 2
Randomized Controlled Study of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy in Stage I/Low-Risk Stage II Colorectal Cancer
ctDNAColorectal Cancer (CRC)Adjuvant Chemotherapy
Fudan University80 enrolled1 locationNCT07562659
Recruiting
Phase 2
Randomized Study of Plasma ctDNA Methylation to Guide Adjuvant Chemotherapy Decisions in High-Risk T3N0 Colorectal Cancer
Colorectal, CancerChemotherapyctDNA
Fudan University340 enrolled1 locationNCT07562711
Recruiting
Phase 1Phase 2
EBV-AST Cell Therapy for EBV-Related Diseases After Stem Cell Transplantation
Post-Transplant Lymphoproliferative DisorderEBV-DNA Viremia
Daihong Liu18 enrolled1 locationNCT07438067
Recruiting
Phase 2
ctDNA-guided Treatment Decision-making
Metastatic Breast Cancer ( HER2 Negative)ctDNA
Fudan University122 enrolled1 locationNCT07394218
Recruiting
Phase 2
ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer
HER2-negative Breast CancerBreast Cancer Early Stage Breast Cancer (Stage 1-3)Hormone Receptor-Positive Breast Cancer+3 more
Peking University People's Hospital393 enrolled1 locationNCT06970912
Recruiting
Phase 2
Using ctDNA to Determine Therapies for Lung Cancer
Non-small Cell Lung CancerCirculating Tumor DNAComplete Surgical Resection
University Health Network, Toronto66 enrolled1 locationNCT04966663
Recruiting
Phase 2
Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures
Dyskeratosis CongenitaFanconi AnemiaBone Marrow Failure+7 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins27 enrolled1 locationNCT04232085
Recruiting
Phase 2
Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome
Mitochondrial DiseasesMitochondrial Metabolism DisordersMitochondrial Encephalomyopathy+2 more
Kenneth Myers, MD200 enrolled1 locationNCT04802707
Recruiting
Phase 2
Olaparib With or Without Durvalumab for DDR Gene Mutated Biliary Tract Cancer Following Platinum-based Chemotherapy
Biliary Tract CancerDNA Damage Repair Deficiency
Asan Medical Center62 enrolled1 locationNCT05222971
Recruiting
Phase 2
Circulating Tumor DNA-guided Neoadjuvant Treatment Strategy for Locally Advanced Rectal Cancer
Circulating Tumor DNALocally Advanced Rectal Carcinoma
Peking Union Medical College Hospital470 enrolled1 locationNCT05601505
Recruiting
Phase 2
Nutritional polypill trial in well subjects in order to assess genome damage
Damage in lymphocyte deoxyribonucleic acid (DNA)
NHMRC250 enrolled1 locationACTRN12607000651482