Dysfunction Clinical Trials in Philadelphia, Pennsylvania

18 recruitingPhiladelphia, Pennsylvania

Showing 118 of 18 trials

Recruiting
Phase 2

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

Cognitive DysfunctionLewy Body DiseaseAmyloid+1 more
Eli Lilly and Company350 enrolled72 locationsNCT07589595
Recruiting
Phase 3

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Phase 3

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer117 enrolled132 locationsNCT07192952
Recruiting
Phase 3

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

MASH - Metabolic Dysfunction-Associated SteatohepatitisNASH - Nonalcoholic Steatohepatitis
Akero Therapeutics, Inc2,150 enrolled322 locationsNCT06528314
Recruiting
Phase 3

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

Metabolic Dysfunction-Associated Steatotic Liver Disease
Eli Lilly and Company4,500 enrolled561 locationsNCT07165028
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
89bio, Inc.762 enrolled303 locationsNCT06419374
Recruiting
Phase 2Phase 3

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled106 locationsNCT05714085
Recruiting
Phase 2

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

Metabolic dysfunction-associated steatohepatitis (MASH)
Regeneron Pharmaceuticals120 enrolled71 locationsNCT05519475
Recruiting

Serranator POINT FORCE Registry

Peripheral Artery Disease (PAD)Dysfunctional AV FistulaDysfunctional AV Graft
Cagent Vascular LLC500 enrolled19 locationsNCT06687590
Recruiting
Not Applicable

A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

Sexual DysfunctionStem Cell Transplant ComplicationsBone Marrow Transplant Complications
Massachusetts General Hospital300 enrolled3 locationsNCT06541002
Recruiting
Phase 2Phase 3

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
Nationwide Children's Hospital500 enrolled32 locationsNCT05267821
Recruiting
Not Applicable

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

Complex Congenital Heart DefectDysfunctional RVOT ConduitPulmonary Valve Insufficiency+1 more
Edwards Lifesciences108 enrolled25 locationsNCT02744677
Recruiting

AERA Pediatrics Registry

Dysfunction of Eustachian Tube
Integra LifeSciences Corporation300 enrolled6 locationsNCT07071298
Recruiting

Surviving Daily Life

Breast CancerBreast CarcinomaBreast Neoplasm+3 more
Thomas Jefferson University30 enrolled1 locationNCT07054723
Recruiting

Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation

Primary Graft DysfunctionLung transplantation
University of Pennsylvania1,150 enrolled1 locationNCT00457847
Recruiting

Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation

Primary Graft DysfunctionLung transplantation
University of Pennsylvania1,150 enrolled1 locationNCT00552357
Recruiting
Not Applicable

HOPS Study: A Conceptual Replication

Attention Deficit Hyperactivity DisorderExecutive Dysfunction
Children's Hospital of Philadelphia240 enrolled1 locationNCT04465708
Recruiting

TEE 3D RV Assessment for SAVR, Mini AVR, and TAVR

Right Ventricular Dysfunction
Thomas Jefferson University78 enrolled1 locationNCT05804240