Phase 4 Dysfunction Clinical Trials

30 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 30 trials

Recruiting
Phase 4

Safety and Efficacy of Collagenase Clostridium Histolyticum After Prior Intralesional PRP for Peyronie's Disease

Genital Diseases, MaleSexual Dysfunctions, PsychologicalPeyronie Disease
University of Miami22 enrolled2 locationsNCT05777031
Recruiting
Phase 4

Postpartum Vaginal Estrogen for Breastfeeding Patients

BreastfeedingVaginal AtrophyPostpartum Sexual Dysfunction
University Hospitals Cleveland Medical Center100 enrolled1 locationNCT05457972
Recruiting
Phase 4

Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation

Endothelial DysfunctionIschemic StrokeCerebrovascular Event+4 more
Duan Chuanzhi354 enrolled1 locationNCT06308952
Recruiting
Phase 4

Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients

Erectile Dysfunctions
Mansoura University500 enrolled11 locationsNCT07391579
Recruiting
Phase 4

Effect of a GnRH Analog on Hepatic Steatosis

EndometriosisMetabolic Dysfunction-Associated Steatotic Liver DiseaseNonalcoholic Fatty Liver
Aristotle University Of Thessaloniki62 enrolled2 locationsNCT06523530
Recruiting
Phase 4

Gastrointestinal Dysmotility on Aspiration Risk

Esophageal Motility DisordersGastric Motor Dysfunction
Boston Children's Hospital120 enrolled1 locationNCT05455359
Recruiting
Phase 4

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting
Phase 4

Resmiterom Efficacy & Safety in Patients With MASH

MASH - Metabolic Dysfunction-Associated Steatohepatitis
Nabiqasim Industries (Pvt) Ltd165 enrolled1 locationNCT07249788
Recruiting
Phase 4

Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection

Sacroiliac Joint DysfunctionSacro-Iliac Spondylosis
University of New Mexico230 enrolled1 locationNCT06268704
Recruiting
Phase 4

Effect of Oral sucRosomIal Iron on exerciSE Capacity and Quality of Life in Patients With Heart Failure

Iron-deficiencyChronic Heart FailureLeft Ventricular Systolic Dysfunction
Raffaele De Caterina60 enrolled1 locationNCT06270498
Recruiting
Phase 4

A Study on the Impact of Bivalirudin Usage During PCI for High-risk Plaques on Post-PCI Coronary Microcirculation.

Coronary Microvascular Dysfunction
Peking University First Hospital70 enrolled1 locationNCT05984537
Recruiting
Phase 4

SGC Stimulation, Perioperative Vascular Reactivity, and Organ Injury in Cardiac Surgery

Endothelial DysfunctionBrain DiseaseVascular Diseases+2 more
Vanderbilt University Medical Center170 enrolled1 locationNCT05812755
Recruiting
Phase 4

Efficacy and Safety of Vespireit, Prolonged-release Tablets, in Patients With Autonomic Dysfunction Syndrome Accompanied by Functional Vertigo

Autonomic DysfunctionVertigo
Valenta Pharm JSC160 enrolled4 locationsNCT06321341
Recruiting
Phase 4

The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease

Stable Angina PectorisCoronary Artery DiseaseCoronary Microvascular Dysfunction+1 more
Tina Vilsbøll124 enrolled3 locationsNCT06606821
Recruiting
Phase 4

Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation

AdenomaParathyroid Dysfunction
University of Alabama at Birmingham417 enrolled1 locationNCT06169735
Recruiting
Phase 4

The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium

Postoperative DeliriumPostoperative Cognitive DysfunctionMajor Noncardiac Surgery
Medical University of Vienna1,332 enrolled2 locationsNCT05990790
Recruiting
Phase 4

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Breast CancerHeart FailureBreast Diseases+10 more
Silesian Centre for Heart Diseases600 enrolled4 locationsNCT05465031
Recruiting
Phase 4

PEnile ReHABilitation After Nerve Sparing Robot-assisted Radical Prostatectomy for Prostate Cancer 2.0 (PEHAB-II)

Erectile Dysfunction Following Radical Prostatectomy
The Netherlands Cancer Institute198 enrolled3 locationsNCT06875258
Recruiting
Phase 4

Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.

Exercise-induced Myocardial DamageRight Ventricular Diastolic Dysfunction
Jessa Hospital30 enrolled1 locationNCT06715748
Recruiting
Phase 4

Timely Recovery After Subclinical Heart Failure

Heart FailureDiastolic Dysfunction
Academisch Ziekenhuis Maastricht130 enrolled1 locationNCT06341101