RecruitingPhase 4NCT07606625

Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment

The Impact of Varenicline Nasal Spray 0.03mg Dry Eye Treatment on Ocular Surface Health, Tear Film Stability, and Ocular Discomfort


Sponsor

University of California, Berkeley

Enrollment

65 participants

Start Date

Mar 6, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to examine the impact of nasal spray treatment on Meibomian gland function and ocular surface health in symptomatic dry eye patients with mild to moderate Meibomian gland dysfunction (MGD).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Varenicline 0.03Mg/Spray Nasal Soln for people with dry eye and meibomian gland dysfunction. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVarenicline 0.03Mg/Spray Nasal Soln

After meeting eligibility criteria and signing informed consent, participants will be dispensed a 3-month supply of varenicline 0.03mg/spray nasal solution. Participants will take the nasal spray home and spray once in each nostril twice daily for 3 months


Locations(1)

U.C. Berkeley Clinical Research Center

Berkeley, California, United States

View Full Details on ClinicalTrials.gov

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NCT07606625


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