Phase 2 Early Breast Cancer Clinical Trials

10 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 110 of 10 trials

Recruiting
Phase 2

NeoAdjuvant Therapy With Trastuzumab-deruxtecan Versus Chemotherapy+Trastuzumab+Pertuzumab in HER2+ Early Breast Cancer

HER2 Positive Early Breast Cancer
West German Study Group702 enrolled44 locationsNCT05704829
Recruiting
Phase 2

Fovinaciclib Plus Aromatase Inhibitors and Dual HER2 Blockade in a Response-Adapted Neoadjuvant Strategy for HR-Positive/HER2-Positive Early Breast Cancer

HR+/HER2- Early Breast Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University100 enrolled3 locationsNCT07616427
Recruiting
Phase 2

Efficacy and Safety of Culmerciclib Plus Aromatase Inhibitors in a Response-Adapted Neoadjuvant Strategy for Highly Proliferative ER-Positive/HER2-Negative Breast Cancer

HR+/HER2- Early Breast Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University45 enrolled1 locationNCT07616453
Recruiting
Phase 2

A Study on the Use of Fluzoparib Combined With Chemotherapy for Neoadjuvant Treatment of HRD-positive, HR+/HER2- Breast Cancer

HR+/HER2- Early Breast Cancer
Xijing Hospital28 enrolled1 locationNCT07162051
Recruiting
Phase 2

Neoadjuvant Trastuzumab-rezetecan Plus Pertuzumab or Nab-Paclitaxel, Carboplatin, Trastuzumab, and Pyrotinib After Suboptimal Response to Neoadjuvant Dual HER2-Targeted Therapy Combined With Chemotherapy in HER2-Positive Early Breast Cancer

HER2 Positive Early Breast Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University200 enrolled1 locationNCT07340398
Recruiting
Phase 2

Mediterranean Diet and Inequality in Early Breast Cancer

Early Breast Cancer
Esbjerg Hospital - University Hospital of Southern Denmark105 enrolled2 locationsNCT07007169
Recruiting
Phase 2

MRI-Guided Neoadjuvant Treatment De-Escalation in Stage II-III TNBC

Early Breast CancerTNBC - Triple-Negative Breast Cancer
Tel-Aviv Sourasky Medical Center54 enrolled2 locationsNCT07327021
Recruiting
Phase 2

Efficacy and Safety of Dalpiciclib With Endocrine Therapy as Adjuvant Treatment in HR+/ HER2- Early Breast Cancer

Early Breast Cancer
The First Affiliated Hospital with Nanjing Medical University1,163 enrolled1 locationNCT06341894
Recruiting
Phase 1Phase 2

Neoadjuvant Therapy Study Guided by Drug Screening in Vitro for Human Epidermal Growth Factor Receptor 2 (HER2) Negative Early Breast Cancer Patients

HER2-negative Early Breast Cancer
Peking University People's Hospital46 enrolled1 locationNCT04836156
Recruiting
Phase 1Phase 2

Neoadjuvant Therapy Study Guided by Drug Screening in Vitro for HER2 Positive Early Breast Cancer Patients

HER2 Positive Early Breast Cancer
Peking University People's Hospital46 enrolled1 locationNCT04750122