Phase 1 Eczema Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1
Ph 1a/1b Single Ascending Dose and Multiple Ascending Dose Study of ARQ-234
EczemaAtopic Dermatitis (AD)
Arcutis Biotherapeutics, Inc.125 enrolled1 locationNCT07453602
Active
Phase 1
A Phase 1, First in Human, Randomised, Double-Blind, Placebo-controlled, Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) Study to Investigate the Safety, Tolerability and Pharmacokinetics of GB-7624 administered subcutaneously in Healthy Adult participants
EczemaAtopic Dermatitis (AD)
Generate Biomedicines Inc.40 enrolled1 locationACTRN12625000229471
Completed
Phase 1
Pivotal in vivo bioequivalence study comparing two formulations of betamethsone OV ointment applied to the skin in healthy male and female volunteers.
Diprosone OV ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited90 enrolled1 locationACTRN12624000621516
Completed
Phase 1
Pivotal in vivo bioequivalence study comparing two formulations of betamethsone ointment applied to the skin in healthy male and female volunteers.
Betamethasone ointment is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited90 enrolled1 locationACTRN12624000107527
Completed
Phase 1
Pivotal in vivo bioequivalence study comparing two formulations of 9-fluoro-11ß-hydroxy- 16ß-methyl-3,20-dioxopregna- 1,4-diene-17,21-diyl dipropanoate cream applied to the skin in healthy male and female volunteers.
9-fluoro-11ß-hydroxy- 16ß-methyl-3,20-dioxopregna- 1,4-diene-17,21-diyl dipropanoate cream is indicated for the topical treatment of eczema and psoriasis in children and adults.
Zenith Technology Corporation Limited90 enrolled1 locationACTRN12623001003662
Completed
Phase 1
Pivotal in vivo bioequivalence study comparing two formulations of 21-acetoxyl group-11 beta-hydroxy-6 Alpha-Methyls-17-propiono Oxy-1,4-pregnen diethylene-3,20-diketone ointment applied to the skin in healthy male and female volunteers.
21-acetoxyl group-11 beta-hydroxy-6 Alpha-Methyls-17-propiono Oxy-1,4-pregnen diethylene-3,20-diketone ointment is indicated for the short term (up to 7 days) treatment of the milder form of eczema, dermatitis and other steroid responsive skin conditions which do not require the use of a more active topical corticosteroid
Zenith Technology Corporation Limited90 enrolled1 locationACTRN12622001421729
Completed
Phase 1
Pivotal in vivo bioequivalence study comparing two formulations of methylprednisolone aceponate fatty ointment applied to the skin in healthy male and female volunteers.
Methylprednisolone aceponate fatty ointment is indicated for the short term (up to 7 days) treatment of the milder form of eczema, dermatitis and other steroid responsive skin conditions which do not require the use of a more active topical corticosteroid in children and adults.
Zenith Technology Corporation Limited90 enrolled1 locationACTRN12620000160932
Completed
Phase 1
Comparative assessment of the absorption of a test formulation of 1 x 10 mg alitretinoin capsule against the innovator 1 x 10 mg alitretinoin capsule conducted under fed conditions in healthy male volunteers.
Bioequivalence study conducted in healthy volunteers comparing a formulation of alitretinoin with no health condition or problem studied.
Although this study is being conducted in healthy volunteers who are not being treated for the condition to which the medicine is used, alitretinoin is a medicine that is used to treat severe chronic eczema that is unresponsive to treatment with potent topical corticosteroids.
Zenith Technology Corp Ltd30 enrolled1 locationACTRN12618000247279
Completed
Phase 1
Comparative assessment of the absorption of a test formulation of 1 x 30 mg alitretinoin capsule against the innovator 1 x 30 mg alitretinoin capsule conducted under fed conditions in healthy male volunteers.
Bioequivalence study conducted in healthy volunteers comparing a formulation of alitretinoin with no health condition or problem studied.
Although this study is being conducted in healthy volunteers who are not being treated for the condition to which the medicine is used, alitretinoin is a medicine that is used to treat severe chronic eczema that is unresponsive to treatment with potent topical corticosteroids.
Zenith Technology Corp Ltd30 enrolled1 locationACTRN12616001221448
Terminated
Phase 1
A Probiotic for Eczema Treatment
Eczema
University of Otago40 enrolled1 locationACTRN12616000022460