Edentulism Clinical Trials

25 recruitingLast updated: May 21, 2026

There are 25 actively recruiting edentulism clinical trials across 15 countries. Studies span Not Applicable, Early Phase 1. Top locations include Madrid, Madrid, Spain, Cairo, Egypt, Al Mansurah, Egypt. Updated daily from ClinicalTrials.gov.


Edentulism Trials at a Glance

25 actively recruiting trials for edentulism are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 20 trials, with the heaviest enrollment activity in Madrid, Cairo, and Al Mansurah. Lead sponsors running edentulism studies include Al-Azhar University, Universidad Complutense de Madrid, and Bluebird International Clinic.

Browse edentulism trials by phase

About Edentulism Clinical Trials

Looking for clinical trials for Edentulism? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Edentulism trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Edentulism clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 25 trials

Recruiting
Not Applicable

Dental Implant Healing With TNF-Alpha Inhibitors

Dental ImplantsEdentulismTNF-alpha Inhibitors
University of Pennsylvania30 enrolled1 locationNCT06538870
Recruiting
Not Applicable

The Effect of Palatal Rugae Design in Complete Denture on Patient Satisfaction and Quality of Life

EdentulismComplete Dentures
Dow University of Health Sciences90 enrolled1 locationNCT07579377
Recruiting
Not Applicable

The Application of a Biphasic Calcium Sulfate Graft Material in Sinus Floor Elevation

Alveolar Bone LossEdentulism Nos
Semmelweis University40 enrolled1 locationNCT06533397
Recruiting
Not Applicable

Comparing Cleaning Tools for Full-Arch Implant-Supported Fixed Prostheses

Edentulism
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University18 enrolled1 locationNCT07474493
Recruiting
Not Applicable

Single-implant Versus Two-implant Mandibular Overdentures

Edentulism
Rola Shadid32 enrolled1 locationNCT07408778
Recruiting
Not Applicable

3D-Printed Implant Overdentures: Comparing Impression Techniques

Edentulism
Mansoura University16 enrolled1 locationNCT07208812
Recruiting
Not Applicable

Platelet-Rich Fibrinogen in Extraction Socket Healing of the Aged

Edentulism
University of Nebraska12 enrolled1 locationNCT06943846
Recruiting
Not Applicable

Accuracy of Digital vs Conventional Denture Impressions: An In Vivo Study

EdentulismComplete DenturesDigital Impression Accuracy+1 more
Mohammed Bin Rashid University of Medicine and Health Sciences10 enrolled1 locationNCT07377890
Recruiting
Not Applicable

Accuracy of Metal Sleeve-Free Fully Guided Implant Surgery

Edentulism
Universidad Complutense de Madrid15 enrolled1 locationNCT07364006
Recruiting
Not Applicable

In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery

Partial edentulismTooth Loss / Rehabilitation
Universidad Complutense de Madrid27 enrolled1 locationNCT07315607
Recruiting
Not Applicable

The Impact of AI-Based Video Education on Denture Care and Oral Health-Related Quality of Life Among Older Adults: A Nursing-Prosthodontic Collaborative Study

Complete EdentulismPartial DenturePartial Edentulism in the Maxilla or in the Mandible
Sherif Aly Sadek50 enrolled1 locationNCT07184320
Recruiting
Not Applicable

Supplementary Implants Supporting Conventional Removable Dental Prosthesis (RDPs) in Kennedy Class I

Partial Edentulism Kennedy Class 1
University Hospital, Basel, Switzerland12 enrolled1 locationNCT04276246
Recruiting

Extra-short vs. Non-extra-short Dental Implants Splinted on the Same Prosthesis

Partial edentulism
Fundación Eduardo Anitua102 enrolled1 locationNCT04927819
Recruiting
Not Applicable

"Patient Satisfaction with Intra-Oral Vs. Extra-Oral Scanned 3D-Printed Dentures: an in Vivo Study"

Complete Edentulism
Cairo University8 enrolled1 locationNCT06846619
Recruiting
Early Phase 1

A Clinical Trial of Dental Device Cemented with Polymethyl Methacrylate (PMMA) Bone Cement

Edentulism
Bluebird International Clinic48 enrolled1 locationNCT06018701
Recruiting
Not Applicable

Evaluation of Bone Changes Around Implants in Patients Treated With All on Four

Dental ImplantEdentulous Alveolar Ridge In MandibleComplete Edentulism+3 more
Al-Azhar University16 enrolled1 locationNCT06723678
Recruiting
Not Applicable

Evaluation of Different Attachments on Implant-Retained Mandibular Overdenture.

EdentulismEdentulism in Lower Jaw
Al-Azhar University10 enrolled1 locationNCT06721377
Recruiting

Examining the Effects of Removable Denture Use in Patients Over 60 Years of Age

EdentulismDenture, CompleteDenture, Partial, Removable
Istanbul University40 enrolled1 locationNCT06688669
Recruiting
Not Applicable

Short Implant Versus Crestal Standard Length Implant to Retain Class 1 Removable Partial Denture.

Bone LossPartial Edentulism Class 1
Menoufia University30 enrolled1 locationNCT06666595
Recruiting
Not Applicable

Patient Satisfaction and Crestal Bone Changes Around One-piece Zirconia(Zr) and Titanium(Ti) in Implant-Retained Mandibular Overdenture

Complete Edentulism
Ain Shams University20 enrolled1 locationNCT06643975