Phase 2 Epidermolysis Bullosa Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 2Phase 3

An International, Multicenter, Randomized, Double-Blind, Parallel Group, Vehicle-Controlled, Phase 2/3 Study With Open-Label Extension Evaluating the Efficacy and Safety of Diacerein 1% Ointment for the Treatment of Generalized Epidermolysis Bullosa Simplex (EBS)

Generalized Epidermolysis Bullosa Simplex
TWi Biotechnology, Inc.80 enrolled36 locationsNCT06073132
Recruiting
Phase 1Phase 2

Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa

Epidermolysis BullosaDystrophic Epidermolysis BullosaEpidermolysis Bullosa Acquisita
M. Peter Marinkovich8 enrolled1 locationNCT06834035
Recruiting
Phase 2

A Phase 2 Study of TCP-25 Gel in Patients With Epidermolysis Bullosa, STEP-study

Dystrophic Epidermolysis BullosaEpidermolysis Bullosa (EB)Junctional Epidermolysis Bullosa
Xinnate AB32 enrolled6 locationsNCT06594393
Recruiting
Phase 1Phase 2

Effect of Ev.FV on Wound Healing in Dystrophic Epidermolysis Bullosa

Wound HealDystrophic Epidermolysis Bullosa
Isfahan University of Medical Sciences20 enrolled1 locationNCT07230223
Recruiting
Phase 2

A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex

Epidermolysis Bullosa Simplex
BioMendics, LLC40 enrolled2 locationsNCT07027345
Recruiting
Phase 2

A 44-week Monocentric Open Study Assessing the Efficacy and Safety of Deucravacitinib in Adults With Inflammatory Genodermatoses

IchthyosisEpidermolysis Bullosa SimplexGenodermatosis+1 more
Centre Hospitalier Universitaire de Nice10 enrolled2 locationsNCT06136403
Recruiting
Phase 1Phase 2

MSC EVs in Dystrophic Epidermolysis Bullosa

Dystrophic Epidermolysis Bullosa
Aegle Therapeutics8 enrolled3 locationsNCT04173650
Recruiting
Phase 2

A 20-Week Study Assessing the Efficacy of Apremilast in Patients with EB Simplex Generalized

Epidermolysis Bullosa SimplexGenodermatosis
Centre Hospitalier Universitaire de Nice20 enrolled4 locationsNCT06509984
Recruiting
Phase 2

Study to Evaluate Safety and Efficacy of ALLO-ASC-SHEET in Subjects With Dystrophic Epidermolysis Bullosa

Dystrophic Epidermolysis Bullosa
Anterogen Co., Ltd.6 enrolled1 locationNCT05157958
Recruiting
Phase 1Phase 2

Gentamicin for Junctional Epidermolysis Bullosa

Junctional Epidermolysis Bullosa
University of Southern California6 enrolled1 locationNCT03526159
Completed
Phase 2

Investigation of cell therapy for recessive dystrophic epidermolysis bullosa (RDEB) in Australia through intradermal injection of allogeneic fibroblasts.

Recessive dystrophic epidermolysis bullosa
Research Infrastructure Support Services (RISS)5 enrolled1 locationACTRN12610000760077