Phase 1 ERP Clinical Trials
29 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 29 trials
Recruiting
Phase 1Phase 2
Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
Herpes Zoster
National Institute of Allergy and Infectious Diseases (NIAID)225 enrolled1 locationNCT05580458
Recruiting
Phase 1Phase 2
A Trial of Lu AG13909 in Participants With Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia
H. Lundbeck A/S42 enrolled17 locationsNCT05669950
Recruiting
Phase 1
A Study to Evaluate the Safety and Pharmacokinetics of AD-116 and AD-1161 in Healthy Adult Male Subjects
Benign Prostatic Hyperplasia
Addpharma Inc.44 enrolled1 locationNCT07444385
Recruiting
Phase 1Phase 2
A Study to Test GlaxoSmithKline's (GSK) Candidate Vaccine-GSK1437173A for Prevention of Shingles in Children With Kidney Transplant
Herpes Zoster
GlaxoSmithKline184 enrolled31 locationsNCT04006808
Recruiting
Phase 1Phase 2
Study to Evaluate the Safety and Immunogenicity of a Lyophilized Herpes Zoster Virus mRNA Vaccine
Herpes ZostermRNA Vaccine
Sinovac Biotech Co., Ltd519 enrolled1 locationNCT07400003
Recruiting
Phase 1Phase 2
Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization.
Herpes Simplex KeratitisCorneal Neovascularization
Second Affiliated Hospital, School of Medicine, Zhejiang University100 enrolled1 locationNCT07329686
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety of Recombinant Herpes Zoster Vaccine for Healthy Individuals
Herpes Zoster (HZ)
Shanghai Institute Of Biological Products645 enrolled1 locationNCT06932523
Recruiting
Phase 1
A Mass Balance Study of [14C] MT1013 in Hemodialysis Subjects With Secondary Hyperparathyroidism
Hemodialysis Subjects With Secondary Hyperparathyroidism
Shaanxi Micot Pharmaceutical Technology Co., Ltd.6 enrolled1 locationNCT07284043
Recruiting
Phase 1Phase 2
Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adults 50 Years of Age and Over
vaccine preventable diseasesHerpes ZosterShingles
Dynavax Technologies Corporation764 enrolled13 locationsNCT06569823
Recruiting
Phase 1
Effetivity of Dutasteride and Aloe Vera Extract Combination on Angiogenesis and Obstruction on Benign Prostatic Hyperplasia
BPH (Benign Prostatic Hyperplasia)
Universitas Diponegoro84 enrolled1 locationNCT07065682
Recruiting
Phase 1
Safety and Immunogenicity of the Recombinant Zoster Vaccine, LYB004 in Adults Aged 40 Years and Older
Herpes Zoster (HZ)
Guangzhou Patronus Biotech Co., Ltd.92 enrolled1 locationNCT06874842
Recruiting
Phase 1
A Phase I Trial of Tumor-Associated Lymph Node T-Cell Injection With Advanced Malignant Solid Tumors
Advanced Solid TumorImmunotherapyTumor Associated Lymph Node T Cell+1 more
Guangzhou FineImmune Biotechnology Co., LTD.32 enrolled1 locationNCT06716619
Recruiting
Phase 1
Safety and Immunogenicity of CVI-VZV-001 for Prevention of Herpes Zoster in Healthy Adults Age 50 Years and Above
vaccine preventable diseasesHerpes Zoster
CHA Vaccine Institute Co., Ltd.32 enrolled2 locationsNCT06137755
Recruiting
Phase 1
A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.
Post-herpetic neuralgiaPainChronic Pain+4 more
iN Therapeutics Co., Ltd.64 enrolled1 locationNCT06218784
Completed
Phase 1
WNTR-VZV-001: A Phase Ib, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety and Tolerability of Solexan™ when Administered Topically to Acute Varicella Zoster Virus (Shingles) Lesions.
Herpes ZosterShingles
Wintermute Biomedical30 enrolled1 locationACTRN12624000075583
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of 2-(diethylamino-N-(2,6-dimethylphenyl)acetamide 5% w/w trandermal patch against the innovator 32-(diethylamino-N-(2,6-dimethylphenyl)acetamide 5% w/w trandermal patch conducted under fasting conditions in healthy male and female volunteers.
2-(diethylamino-N-(2,6-dimethylphenyl)acetamide is used as a local anaesthetic. It is indicated for symptomatic relief of nerve pain associated with medically diagnosed post-herpetic neuralgia (post-shingles pain).
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12622000141741
Not Yet Recruiting
Phase 1
A study comparing Brincidofovir administered as an oral suspension versus Intravenous Formulation in Japanese and Non-Japanese Adult Volunteers
Viral Infection - orthopoxvirusesViral Infection - polyomavirusesViral Infection - human herpesviruses (HHV)+2 more
Chimerix Inc.36 enrolled1 locationACTRN12618002011268
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of tamsulosin tablet against the innovator tamsulosin tablet conducted under fasting condition and at steady state in healthy male and female volunteers.
Tamsulosin is indicated for the relief of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12618001147279
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of tamsulosin tablet against the innovator tamsulosin tablet conducted under fed condition in healthy male and female volunteers.
Tamsulosin is indicated for the relief of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).
Zenith Technology Corp Ltd28 enrolled1 locationACTRN12618001051235
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of tamsulosin tablet against the innovator tamsulosin tablet conducted under fasting condition in healthy male and female volunteers.
Tamsulosin is indicated for the relief of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).
Zenith Technology Corporation Limited28 enrolled1 locationACTRN12618000776202