Phase 2 ERP Clinical Trials

50 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 50 trials

Recruiting
Phase 2Phase 3

A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

Congenital Adrenal HyperplasiaClassic Congenital Adrenal Hyperplasia
Crinetics Pharmaceuticals Inc.153 enrolled43 locationsNCT07159841
Recruiting
Phase 2

Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate Cancer

Prostatic HyperplasiaUrinary Urge IncontinenceStress Urinary Incontinence
National Cancer Institute (NCI)41 enrolled1 locationNCT06161506
Recruiting
Phase 2

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

End Stage Renal Disease on DialysisHyperphosphatemiaChronic Kidney Disease Requiring Chronic Dialysis
R1 Therapeutics168 enrolled31 locationsNCT06712654
Recruiting
Phase 2

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

Breast CarcinomaEstrogen Receptor-Positive Breast CarcinomaBreast Ductal Carcinoma in Situ+3 more
National Cancer Institute (NCI)200 enrolled11 locationsNCT06184750
Recruiting
Phase 1Phase 2

Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population

Herpes Zoster
National Institute of Allergy and Infectious Diseases (NIAID)225 enrolled1 locationNCT05580458
Recruiting
Phase 2

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

Breast CarcinomaBreast Ductal Carcinoma in SituBreast Atypical Hyperplasia+1 more
National Cancer Institute (NCI)80 enrolled4 locationsNCT05941520
Recruiting
Phase 2

Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window Trial

Endometrial Endometrioid AdenocarcinomaEndometrial Hyperplasia
New Mexico Cancer Research Alliance140 enrolled4 locationsNCT07436793
Recruiting
Phase 2

An Extension Study to Evaluate Safety and Efficacy of Atumelnant in Participants With Congenital Adrenal Hyperplasia

Congenital Adrenal HyperplasiaClassic Congenital Adrenal Hyperplasia
Crinetics Pharmaceuticals Inc.200 enrolled13 locationsNCT06712823
Recruiting
Phase 2Phase 3

Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia

Overweight and ObesityAtypical Endometrial HyperplasiaFertility Issues
Xiaojun Chen172 enrolled1 locationNCT05316493
Recruiting
Phase 2Phase 3

Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors

Primary HyperparathyroidismParathyroid CancerMultiple Endocrine Neoplasias+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)193 enrolled1 locationNCT07444723
Recruiting
Phase 2

Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)

KSHV Inflammatory Cytokine Syndrome (KICS)Kaposi Sarcoma Herpesvirus -Associated Multicentric Castleman Disease
National Cancer Institute (NCI)75 enrolled1 locationNCT06052618
Recruiting
Phase 2

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

Breast CarcinomaBreast Ductal Carcinoma in SituBreast Atypical Hyperplasia+1 more
National Cancer Institute (NCI)66 enrolled3 locationsNCT06195306
Recruiting
Phase 2

Y-4 to Treat the Postherpetic Neuralgia

Postherpetic NeuralgiaPregabalinY-4
Neurodawn Pharmaceutical Co., Ltd.160 enrolled1 locationNCT07275762
Recruiting
Phase 2

Intrauterine Injection of Type III Collage in FST of EC/AEH

Endometrial CancerAtypical Endometrial Hyperplasia
Wang Jianliu30 enrolled1 locationNCT07377734
Recruiting
Phase 2

New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia

Lower Urinary Track SymptomsBPH (Benign Prostatic Hyperplasia)
Beth Israel Deaconess Medical Center242 enrolled1 locationNCT06944145
Recruiting
Phase 2

Pharmacokinetics, Safety and Tolerability of Crinecerfont in Participants With Congenital Adrenal Hyperplasia Who Are Less Than 2 Years Old

Congenital Adrenal Hyperplasia
Neurocrine Biosciences6 enrolled3 locationsNCT07187375
Recruiting
Phase 1Phase 2

A Trial of Lu AG13909 in Participants With Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia
H. Lundbeck A/S42 enrolled17 locationsNCT05669950
Recruiting
Phase 1Phase 2

A Study to Test GlaxoSmithKline's (GSK) Candidate Vaccine-GSK1437173A for Prevention of Shingles in Children With Kidney Transplant

Herpes Zoster
GlaxoSmithKline184 enrolled31 locationsNCT04006808
Recruiting
Phase 2

Phase II Study to Evaluate the Safety and Efficacy of Prostatic Artery Embolization

Prostate CarcinomaBenign Prostatic Hyperplasia
H. Lee Moffitt Cancer Center and Research Institute26 enrolled1 locationNCT04879940
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Immunogenicity of a Lyophilized Herpes Zoster Virus mRNA Vaccine

Herpes ZostermRNA Vaccine
Sinovac Biotech Co., Ltd519 enrolled1 locationNCT07400003