Phase 1 EUS Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1Phase 2
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
Staphylococcus Aureus
AstraZeneca231 enrolled42 locationsNCT06749457
Recruiting
Phase 1
Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)
Pelizaeus-Merzbacher Disease
Ionis Pharmaceuticals, Inc.24 enrolled7 locationsNCT06150716
Recruiting
Phase 1
Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome
Staphylococcus AureusMicrobial ColonizationNeonatal Infection
Johns Hopkins University175 enrolled1 locationNCT06283355
Recruiting
Phase 1
UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells
Batten DiseaseAdrenoleukodystrophyPelizaeus-Merzbacher Disease+9 more
Joanne Kurtzberg, MD40 enrolled1 locationNCT02254863
Recruiting
Phase 1
Administering NMT to Reestablish Infant Nasal Microbiome Diversity Following Intranasal Mupirocin Treatment
Microbial ColonizationStaphylococcal Aureus InfectionPediatric Infection+2 more
Johns Hopkins University175 enrolled1 locationNCT06805994
Recruiting
Phase 1
First-in-man Single-dose and Multiple Dose Study to Evaluate the Safety, Tolerability and Efficacy ofHY-133
Staphylococcus Aureus
University Hospital Tuebingen52 enrolled2 locationsNCT06290557
Recruiting
Phase 1Phase 2
Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section
Postoperative Ileus
Assiut University90 enrolled1 locationNCT05654649
Completed
Phase 1
A Phase Ib, Randomised, Placebo-Controlled, Double-Blind Study to Evaluate Potential Benefits of Two Concentrations of Betahistine Dihydrochloride Spray Administered as a Single Intranasal Dose in Adult Male and Female Volunteers with Eustachian Tube Dysfunction
Allergic rhinitis (hay fever)Eustachian tube dysfunctionRhinitis
Otifex Therapeutics24 enrolled1 locationACTRN12615000657527
Completed
Phase 1
A Phase 1 Single-Center, Open-Label Study to Evaluate the Safety and Pharmacokinetics of a Candidate Topical Antimicrobial (NEO101) among Healthy Adult Men
Open-label safety pharmacokinetic study in healthy adult men of topical antimicrobial being developed for the indication of nasal carriage of Staphylococcus aureus.
Neosil, Inc5 enrolled1 locationACTRN12607000260426