femur fracture Clinical Trials

15 recruitingLast updated: May 11, 2026

There are 15 actively recruiting femur fracture clinical trials across 8 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Toronto, Ontario, Canada, Gainesville, Florida, United States, Hamilton, Ontario, Canada. Updated daily from ClinicalTrials.gov.


femur fracture Trials at a Glance

15 actively recruiting trials for femur fracture are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Toronto, Gainesville, and Hamilton. Lead sponsors running femur fracture studies include Unity Health Toronto, McGill University, and London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's.

Browse femur fracture trials by phase

Treatments under study

About femur fracture Clinical Trials

Looking for clinical trials for femur fracture? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new femur fracture trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about femur fracture clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Not Applicable

DIFFIR - Geriatric Distal Femur Fixation Versus Replacement

Distal Femur Fracture
Unity Health Toronto140 enrolled1 locationNCT04076735
Recruiting

Frailty and Nottingham Hip Fracture Score for Predicting 90-Day Mortality After Hip Fracture Surgery

Proximal femur fractureFrailtyHip Fracture
Trakya University200 enrolled1 locationNCT07481188
Recruiting
Not Applicable

Effect of Remimazolam and Propofol on Postoperative Delirium

femur fractureKnee OsteoarthritisHip Fractures
Inje University82 enrolled1 locationNCT05514405
Recruiting
Not Applicable

Carbo-fix Lateral Plate Devices and Standard Plate-Nail Constructs in Distal Femur Fractures

Distal Femur Fracture
University of Missouri-Columbia100 enrolled1 locationNCT07280169
Recruiting
Not Applicable

pDIFFIR: Geriatric Periprosthetic DIstal Femur: FIxation Versus Replacement

Distal Femur FracturePeriprosthetic Fracture Around Prosthetic Joint Implant KneeKnee Fracture
Unity Health Toronto148 enrolled1 locationNCT05805774
Recruiting

ZNN Bactiguard Antegrade Femoral Nails PMCF Study

femur fractureOsteotomy
Zimmer Biomet100 enrolled2 locationsNCT05339360
Recruiting
Phase 2Phase 3

Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery

femur fracturePost Operative PainHypotension+1 more
Sahiwal medical college sahiwal70 enrolled1 locationNCT06568770
Recruiting
Not Applicable

Single vs. Dual Implant Fixation for Distal Femur Fractures in Older or Compromised Adults

Distal Femur Fractures
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's44 enrolled2 locationsNCT06944964
Recruiting
Not Applicable

Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)

Distal Femur Fracture
University of Florida100 enrolled1 locationNCT05792189
Recruiting

Quebec Registry for Atypical Femur Fractures

Atypical Femur Fracture
McGill University150 enrolled1 locationNCT02150850
Recruiting
Not Applicable

Opioid-Free Pain Treatment in Trauma Patients

Femoral shaft fracturelisfranc injuriesProximal humerus fractures+19 more
University of Kansas Medical Center250 enrolled1 locationNCT06078371
Recruiting

Testing the effectiveness and cost-effectiveness of Bounce Back, a tailored action-oriented discharge planning intervention for older hip fracture patients: A randomised controlled trial

Neck of femur fracture (Hip fracture)
University of Newcastle520 enrolled1 locationACTRN12624000730505
Recruiting

Atypical Fracture Cohort Study

Atypical Femur FractureAtypical Subtrochanteric FractureOsteoporosis With AFf
University Health Network, Toronto300 enrolled3 locationsNCT01747291
Recruiting

Randomized controlled trial to compare functional outcomes between LOcking compression Plates and Retrograde Intramedullary Nails in distal femur fractures

Simple extra-articular Distal femur fracture (AO classification type 33A2/3)
Syed Imran Bukhari96 enrolled1 locationACTRN12622000229774
Recruiting

Distal Femur Fracture Healing in the Elderly Using Far Cortical Locking Screws.

Distal Femur Fracture
Royal Perth Hospital (Professor Markus Kuster)100 enrolled10 locationsACTRN12617000493347