Phase 1 Fever Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1Phase 2
Immunogenicity of Yellow Fever Vaccine 17D in Adults With Prior 17D Vaccination
Yellow FeverImmunization; Infection
Oregon Health and Science University35 enrolled1 locationNCT05859490
Recruiting
Phase 1
Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever
VaccineCrimean-Congo Hemorrhagic Fever
HDT Bio48 enrolled1 locationNCT06799013
Recruiting
Phase 1
A Trial to Evaluate the Safety and Immunogenicity of an Investigational Vaccine for the Prevention of Yellow Fever, and of an Investigational Vaccine for the Prevention of Rabies, in Healthy Adults
Yellow FeverRabies
AstriVax Therapeutics144 enrolled2 locationsNCT06998004
Withdrawn
Phase 1
Comparative assessment of the absorption of a generic formulation of a combination N-(4-hydroxyphenyl)acetamide/(RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid oral suspension against two innovator formulations administered simultaneously of N-(4-hydroxyphenyl)acetamide oral suspension and (RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid oral suspension conducted under fasting conditions in healthy volunteers.
(RS)-2-(4-(2-Methylpropyl)phenyl)propanoic acid is a nonsteroidal anti-inflammatory drug used for the temporary relief of fever, pain associated with teething, toothache, earache, sore throat, headache, minor ache, sprain, strain, cold and flu.N-(4-hydroxyphenyl)acetamide is an effective analgesic and antipyretic. It is indicated for the temporary relief of pain, discomfort associated with teething, headache, earache, immunisation, toothache, cold and flu, and it reduces fever.
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12621001446853
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of paracetamol / ibuprofen / doxylamine tablet against the innovator paracetamol / codeine phosphate hemihydrate / doxylamine succinate tablets and paracetamol / ibuprofen tablet conducted under fasting conditions in healthy male and female volunteers
PainInflammationAllergy+1 more
Zenith Technology Corporation Limited24 enrolled1 locationACTRN12619001017112
Completed
Phase 1
How does the absorption of benzathine penicillin G (BPG) used for Group A Streptococcus (GAS) treatment and secondary prophylaxis for rheumatic fever (RF) differ when injected into the fat layer compared to injection in the muscle in healthy adult men?
Group A streptococcal infectionsRheumatic feverSyphilis
Telethon Kids Institute15 enrolled1 locationACTRN12618001435279
Completed
Phase 1
A study to determine the safety and tolerability of graded doses of the drug LHF-535 (LHF-535-SDD) in healthy volunteers.
Lassa Hemorrhagic Fever
Clinical Network Services (CNS) Pty Ltd56 enrolled1 locationACTRN12618001342202
Completed
Phase 1
A first in Human single-Center Study To Evaluate the effectiveness and Safety Of A Live Attenuated Dengue Vaccine (KD-382) In Healthy Adults
Dengue Fever
KM Biologics Co., Ltd.60 enrolled1 locationACTRN12618001027202
Completed
Phase 1
Phase I study to evaluate the safety and tolerability of single and multiple doses of intranasal pentosan polysulfate (Rhinosul 'Trademark') in healthy subjects
Hay feverAllergic Rhinitis
Paradigm Biopharmaceuticals18 enrolled1 locationACTRN12616000676415
Completed
Phase 1
A Phase Ib, Randomised, Placebo-Controlled, Double-Blind Study to Evaluate Potential Benefits of Two Concentrations of Betahistine Dihydrochloride Spray Administered as a Single Intranasal Dose in Adult Male and Female Volunteers with Eustachian Tube Dysfunction
Allergic rhinitis (hay fever)Eustachian tube dysfunctionRhinitis
Otifex Therapeutics24 enrolled1 locationACTRN12615000657527