Phase 1 FFI Clinical Trials
32 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 32 trials
Recruiting
Phase 1
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Moderate or Severe Hepatic Impairment
Liver DiseasesHepatic Insufficiency
Incyte Corporation16 enrolled4 locationsNCT07559474
Recruiting
Phase 1
A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.
Hepatic Insufficiency
Eli Lilly and Company36 enrolled3 locationsNCT07401862
Recruiting
Phase 1
Fecal Microbiota Transplantation in an Expanded Ulcerative Colitis Population
Inflammatory Bowel DiseasesUlcerative ColitisClostridioides Difficile Infection
University of Alberta85 enrolled2 locationsNCT07401680
Recruiting
Phase 1Phase 2
Evaluation of EXL01, a New Live Biotherapeutic Product to Prevent Recurrence of Clostridioides Difficile Infection in High-risk Patients
Clostridioides Difficile InfectionRecurrent Infection
Hospices Civils de Lyon56 enrolled9 locationsNCT06306014
Recruiting
Phase 1
A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems
Hepatic Insufficiency
Boehringer Ingelheim44 enrolled3 locationsNCT06957756
Recruiting
Phase 1
First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase Insufficiency
Luteal Phase InsuffiencyProgesterone Delivery
Calla Lily Clinical Care Ltd20 enrolled1 locationNCT07136922
Recruiting
Phase 1
Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis
Cystic Fibrosis-related DiabetesPancreatic Insufficiency
University of Pennsylvania15 enrolled2 locationsNCT06995651
Recruiting
Phase 1
A Trial of Hydroxynidone Capsules in Single-dose Administration for Patients With Renal Insufficiency
Renal Insufficiency, Chronic
Beijing Continent Pharmaceutical Co, Ltd.56 enrolled1 locationNCT07262333
Recruiting
Phase 1
Intestinal Microbiota Transplantation in Patients Undergoing Colon Resection
Recurrent Clostridioides difficile infectionColonic Surgery
University of Minnesota40 enrolled1 locationNCT06370884
Recruiting
Phase 1Phase 2
RIG 101 Trial in Healthy Adults and Adults With Asthma
healthy adult participantsSafety and EfficacyAsthma Exacerbation
RIGImmune Inc.82 enrolled2 locationsNCT07488897
Recruiting
Phase 1Phase 2
FMT in Patients With Recurrent CDI and Ulcerative Colitis: Single Infusion Versus Sequential Approach
Ulcerative ColitisClostridium Difficile
Fondazione Policlinico Universitario Agostino Gemelli IRCCS64 enrolled1 locationNCT06071312
Recruiting
Phase 1
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
Kidney DiseaseRenal ImpairmentRenal Insufficiency, Chronic+3 more
Eli Lilly and Company28 enrolled2 locationsNCT07426380
Recruiting
Phase 1
A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function
Renal Insufficiency
Eli Lilly and Company32 enrolled4 locationsNCT07137689
Recruiting
Phase 1Phase 2
JAG201 Gene Therapy Study in Children & Adults With SHANK3 Haploinsufficiency
Phelan-McDermid SyndromeSHANK3 Haploinsufficiency
Jaguar Gene Therapy, LLC6 enrolled3 locationsNCT06662188
Recruiting
Phase 1Phase 2
Phase 1/2 Study of HYP-2090PTSA in Patients With Advanced Solid Tumors Harboring KRAS Mutation
EfficacySafetyTolerability
Sichuan Huiyu Pharmaceutical Co., Ltd257 enrolled6 locationsNCT06243354
Recruiting
Phase 1Phase 2
Phase 1/2 Clinical Study of HY07121 Powder for Solution for Infusion in Patients With Advanced Solid Tumors
EfficacySafetyTolerability
Sichuan Huiyu Pharmaceutical Co., Ltd258 enrolled1 locationNCT06639256
Recruiting
Phase 1
Home-based Vision Therapy
convergence insufficiency
VA Office of Research and Development45 enrolled1 locationNCT06886737
Recruiting
Phase 1Phase 2
Modafinil to Improve Fatiguability
Cancer-related Cognitive DifficultiesFatigueCancer-related Problem/Condition
Ottawa Hospital Research Institute40 enrolled1 locationNCT05333250
Recruiting
Phase 1Phase 2
Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults
ObesityInsufficient Sleep
University of Minnesota90 enrolled1 locationNCT06226077
Recruiting
Phase 1
A Study of the Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment
HealthyHepatic Insufficiency
Eli Lilly and Company32 enrolled3 locationsNCT07165002