Phase 1 FFI Clinical Trials
24 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 24 trials
Recruiting
Phase 1
A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems
Hepatic Insufficiency
Boehringer Ingelheim44 enrolled3 locationsNCT06957756
Recruiting
Phase 1
First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase Insufficiency
Luteal Phase InsuffiencyProgesterone Delivery
Calla Lily Clinical Care Ltd20 enrolled1 locationNCT07136922
Recruiting
Phase 1
Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis
Cystic Fibrosis-related DiabetesPancreatic Insufficiency
University of Pennsylvania15 enrolled2 locationsNCT06995651
Recruiting
Phase 1
A Study of Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.
Hepatic Insufficiency
Eli Lilly and Company36 enrolled3 locationsNCT07401862
Recruiting
Phase 1Phase 2
FMT in Patients With Recurrent CDI and Ulcerative Colitis: Single Infusion Versus Sequential Approach
Ulcerative ColitisClostridium Difficile
Fondazione Policlinico Universitario Agostino Gemelli IRCCS64 enrolled1 locationNCT06071312
Recruiting
Phase 1
A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function
Renal Insufficiency
Eli Lilly and Company32 enrolled4 locationsNCT07137689
Recruiting
Phase 1Phase 2
Evaluation of EXL01, a New Live Biotherapeutic Product to Prevent Recurrence of Clostridioides Difficile Infection in High-risk Patients
Clostridioides Difficile InfectionRecurrent Infection
Hospices Civils de Lyon56 enrolled9 locationsNCT06306014
Recruiting
Phase 1Phase 2
JAG201 Gene Therapy Study in Children & Adults With SHANK3 Haploinsufficiency
Phelan-McDermid SyndromeSHANK3 Haploinsufficiency
Jaguar Gene Therapy, LLC6 enrolled3 locationsNCT06662188
Recruiting
Phase 1Phase 2
Phase 1/2 Study of HYP-2090PTSA in Patients With Advanced Solid Tumors Harboring KRAS Mutation
EfficacySafetyTolerability
Sichuan Huiyu Pharmaceutical Co., Ltd257 enrolled6 locationsNCT06243354
Recruiting
Phase 1Phase 2
Phase 1/2 Clinical Study of HY07121 Powder for Solution for Infusion in Patients With Advanced Solid Tumors
EfficacySafetyTolerability
Sichuan Huiyu Pharmaceutical Co., Ltd258 enrolled1 locationNCT06639256
Recruiting
Phase 1Phase 2
Modafinil to Improve Fatiguability
Cancer-related Cognitive DifficultiesFatigueCancer-related Problem/Condition
Ottawa Hospital Research Institute40 enrolled1 locationNCT05333250
Recruiting
Phase 1Phase 2
Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults
ObesityInsufficient Sleep
University of Minnesota90 enrolled1 locationNCT06226077
Recruiting
Phase 1
A Study of the Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment
HealthyHepatic Insufficiency
Eli Lilly and Company32 enrolled3 locationsNCT07165002
Recruiting
Phase 1
Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial
EfficacySafetySpinal Cord Injury+4 more
XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.12 enrolled1 locationNCT06976229
Recruiting
Phase 1
MTC Versus FMT in for RCDI
Clostridiodies Difficile Infections
Icahn School of Medicine at Mount Sinai60 enrolled1 locationNCT05911997
Recruiting
Phase 1Phase 2
Evaluation of Clinical, Perceived and Instrumental Efficacy of a Scar Gel in Preventing Hypertrophic Scars
Safety and EfficacyTopical AdministrationAcceptability Study+1 more
Herbarium Laboratorio Botanico Ltda80 enrolled2 locationsNCT06751433
Recruiting
Phase 1Phase 2
Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency
Premature Ovarian Insufficiency
Yan Hongli50 enrolled1 locationNCT07115082
Recruiting
Phase 1
A Pharmacokinetics and Safety Study of Azvudine Tablets in Subjects With Mild-To-Moderate GFR Decline in Renal Insufficiency and in Healthy Subjects
Renal Insufficiency
Henan Genuine Biotech Co., Ltd.40 enrolled1 locationNCT07001436
Recruiting
Phase 1Phase 2
Probiotic Supplementation and Disease Progression in CKD: A Randomized Trial
Kidney Disease, ChronicRenal Insufficiency, ChronicGut Dysbiosis+1 more
Mansoura University72 enrolled1 locationNCT06863194
Recruiting
Phase 1
A Study to Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic Function
Hepatic Insufficiency
X4 Pharmaceuticals48 enrolled4 locationsNCT06858696