gastrointestinal disorder Clinical Trials

27 recruitingLast updated: June 18, 2026

There are 27 actively recruiting gastrointestinal disorder clinical trials across 14 countries. Studies span Not Applicable, Phase 2, Phase 1. Top locations include Milwaukee, Wisconsin, United States, Philadelphia, Pennsylvania, United States, Cincinnati, Ohio, United States. Updated daily from ClinicalTrials.gov.


gastrointestinal disorder Trials at a Glance

27 actively recruiting trials for gastrointestinal disorder are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 15 trials, with the heaviest enrollment activity in Milwaukee, Philadelphia, and Cincinnati. Lead sponsors running gastrointestinal disorder studies include Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Medical College of Wisconsin, and Sheffield Teaching Hospitals NHS Foundation Trust.

Browse gastrointestinal disorder trials by phase

Treatments under study

About gastrointestinal disorder Clinical Trials

Looking for clinical trials for gastrointestinal disorder? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new gastrointestinal disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about gastrointestinal disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting
Not Applicable

High Resolution Manometry After Partial Fundoplication for Gastro-oesophageal Reflux

Gastroesophageal RefluxEsophageal Motility DisordersUpper Gastrointestinal Disorder
Prof Urs Zingg100 enrolled1 locationNCT05132816
Recruiting
Phase 2

Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)

Short Bowel SyndromeFunctional Gastrointestinal DisordersPost-Op Complication+2 more
Napo Therapeutics, S.p.A.18 enrolled8 locationsNCT06904872
Recruiting
Not Applicable

Mechanism of FODMAP Restriction on FGID Patients

Functional DyspepsiaIrritable Bowel Syndrome (IBS)Functional Gastrointestinal Disorders (FGIDs)
Universiti Kebangsaan Malaysia Medical Centre60 enrolled1 locationNCT07000227
Recruiting
Not Applicable

Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases

Environmental ExposurePollution; ExposureFunctional Gastrointestinal Disorders+13 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS280 enrolled2 locationsNCT06529913
Recruiting
Not Applicable

Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome

Postural Orthostatic tachycardia SyndromeFunctional Gastrointestinal DisordersAutonomic Nervous System Disease+2 more
Medical College of Wisconsin90 enrolled1 locationNCT05212129
Recruiting
Not Applicable

Autonomic Reactivity and Personalized Neurostimulation

DysautonomiaFunctional DyspepsiaFunctional Gastrointestinal Disorders (FGIDs)+1 more
Medical College of Wisconsin120 enrolled1 locationNCT06863207
Recruiting

BSGM to Evaluate Patients With GI Symptoms

Functional Gastrointestinal DisordersGastroparesisDyspepsia and Other Specified Disorders of Function of Stomach+1 more
Children's Hospital of Philadelphia685 enrolled5 locationsNCT05880199
Recruiting

Institutional Registry of Rare Diseases

ParagangliomaPheochromocytomaAmyloidosis+23 more
Hospital Italiano de Buenos Aires380 enrolled1 locationNCT06573723
Recruiting
Not Applicable

Performance Characteristics and Technical Outcomes of Single-use vs. Reusable Gastroscopes Evaluated in the OR

Upper Gastrointestinal Disorder
Zealand University Hospital700 enrolled1 locationNCT06581016
Recruiting

Dupilumab Therapy for EGIDs

Eosinophilic Gastrointestinal Disorders (EGIDs)
Children's Hospital of Fudan University20 enrolled1 locationNCT07257835
Recruiting

OMEGA: Outcome Measures in Eosinophilic Gastrointestinal Disorders Across the Ages

eosinophilic esophagitisEosinophilic GastritisEosinophilic Gastrointestinal Disorders (EGIDs)+2 more
Children's Hospital Medical Center, Cincinnati1,350 enrolled19 locationsNCT02523118
Recruiting
Not Applicable

Effect of Fecal Microbiota Transplantation (FMT) in Pediatric Functional Gastrointestinal Disorders

Functional Gastrointestinal Disorders
Biao Zou100 enrolled1 locationNCT05753774
Recruiting
Not Applicable

A Heart Rate Variability (HRV) Biofeedback Training in Functional Gastrointestinal Disorders (FGID)

Functional Gastrointestinal Disorders (FGIDs)
Fondazione Don Carlo Gnocchi Onlus40 enrolled1 locationNCT06687057
Recruiting

The effect of gastric surgeries (anti-reflux or bariatric) on symptoms and gastric activity using Gastric Alimetry in patients indicated for gastric surgery

Post-surgical functional gastrointestinal disordersGastric dysmotilityChronic gastrointestinal symptoms following anti-reflux or bariatric surgery+1 more
Western Sydney University20 enrolled1 locationACTRN12625000796482
Recruiting
Not Applicable

Prevalence of FGIDs and Probiotics Study

Functional Gastrointestinal DisordersInfant Conditions
Chulalongkorn University512 enrolled1 locationNCT06309199
Recruiting
Not Applicable

Performance Characteristics and Technical Outcomes of Single-use Gastroscopes Used Bedside Versus Reusable Gastroscopes Used in the Endoscopy Unit Evaluated in Subacute Patients

Upper Gastrointestinal Disorder
Zealand University Hospital180 enrolled1 locationNCT06771102
Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Multiple Endocrine Neoplasia Type 1Multiple Endocrine Neoplasia Type 2Rare Disorders+337 more
Sanford Health20,000 enrolled2 locationsNCT01793168
Recruiting
Not Applicable

The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise

Other Gastrointestinal DisordersCramp, Abdominal
Old Dominion University90 enrolled1 locationNCT05217589
Recruiting

Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.

DiarrheaFunctional Gastrointestinal DisordersGastroesophageal Reflux+4 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS71 enrolled1 locationNCT06031025
Recruiting
Not Applicable

Evolution of Functional Gastrointestinal Disorders in Infants Fed With a New Infant Formula

Functional Gastrointestinal Disorders
United Pharmaceuticals139 enrolled4 locationsNCT06488274