Phase 1 Gliosarcoma Clinical Trials

10 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 110 of 10 trials

Recruiting
Phase 1

A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma

GlioblastomaAnaplastic AstrocytomaAnaplastic Oligodendroglioma+2 more
University of Nebraska24 enrolled1 locationNCT05698524
Recruiting
Phase 1

A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment.

GlioblastomaGliosarcoma, AdultGlioblastoma - Category
University College, London16 enrolled1 locationNCT07134842
Recruiting
Phase 1

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

GlioblastomaGliosarcoma
Memorial Sloan Kettering Cancer Center60 enrolled10 locationsNCT06934889
Recruiting
Phase 1

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Recurrent GlioblastomaRecurrent Malignant GliomaRecurrent Gliosarcoma+2 more
M.D. Anderson Cancer Center36 enrolled1 locationNCT03896568
Recruiting
Phase 1

Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM

Recurrent Supratentorial GlioblastomaSupratentorial GliosarcomaRecurrent Gliosarcoma
M.D. Anderson Cancer Center25 enrolled1 locationNCT04991870
Recruiting
Phase 1Phase 2

Study of Pembrolizumab and M032 (NSC 733972)

Glioblastoma MultiformeAnaplastic AstrocytomaGliosarcoma
University of Alabama at Birmingham28 enrolled1 locationNCT05084430
Recruiting
Phase 1

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Central Nervous System NeoplasmsGlioblastomaOligodendroglioma+20 more
Jazz Pharmaceuticals102 enrolled1 locationNCT04541082
Recruiting
Phase 1Phase 2

Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma

Recurrent GlioblastomaRecurrent Gliosarcoma
M.D. Anderson Cancer Center6 enrolled1 locationNCT05039281
Recruiting
Phase 1

Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcoma

GlioblastomaGliosarcoma
M.D. Anderson Cancer Center29 enrolled1 locationNCT04555577
Recruiting
Phase 1

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Recurrent Childhood Lymphoblastic LymphomaRecurrent Childhood Acute Myeloid LeukemiaRefractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive+15 more
Florida International University65 enrolled1 locationNCT05857969