Phase 2 Glomerulonephritis Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 2

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

Glomerulonephritis, IGAImmunoglobulin A Nephropathy
Novartis Pharmaceuticals20 enrolled18 locationsNCT06797518
Recruiting
Phase 2

Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Autoimmune DiseaseProteinuriaGlomerular Disease+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled2 locationsNCT00977977
Recruiting
Phase 2

Obinutuzumab in Treatment of Fibrillary Glomerulonephritis

Fibrillary Glomerulonephritis
Mayo Clinic20 enrolled1 locationNCT06295770
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

Focal Segmental GlomerulosclerosisGlomerulonephritis Minimal Lesion
Sanofi84 enrolled69 locationsNCT06500702
Recruiting
Phase 2

Rescue of Nephrons With ALE.F02 (RENAL-F02)

Glomerulonephritis Rapidly Progressive
Alentis Therapeutics AG80 enrolled49 locationsNCT06047171
Recruiting
Phase 2

Daratumumab for Treatment of Proliferative Glomerulonephritis With Monoclonal Immune Deposits

Proliferative Glomerulonephritis With Monoclonal IgG Deposits
Mayo Clinic40 enrolled4 locationsNCT05654506
Recruiting
Phase 2

Safety and Efficacy Study of OMS906 in Patients With C3G and ICGN

C3 GlomerulopathyIdiopathic Immune Complex-Mediated Glomerulonephritis
Omeros Corporation20 enrolled6 locationsNCT06209736
Recruiting
Phase 2

Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

C3 GlomerulopathyDense Deposit DiseaseMembranoproliferative Glomerulonephritis+2 more
Region Skane30 enrolled4 locationsNCT04183101
Recruiting
Phase 2

Effect of Finerenone in Patients With Non-diabetic Glomerulonephritis

Glomerulonephritis
Alexandria University100 enrolled1 locationNCT06835322
Recruiting
Phase 2

The Effect of Daratumumab in Patients with Monoclonal Gammopathy of Renal Significance (MGRS) in Finland

Kidney FailureParaproteinemiasGlomerulonephritis
Helsinki University Central Hospital30 enrolled1 locationNCT06889948
Recruiting
Phase 2Phase 3

Evaluation of Captopril and Nifedipine in Treatment of Hypertension in Children with Post-streptoccal Acute Glomerulonephritis with Hypertension- A Randomized Control Trial

Control of Blood Pressure in Patients with Post-sterptococcal Acute Glomerulonephritis (PSAGN)Renal profiles in patients with Post-streptococcal Acute Glomerulonephritis (PSAGN)
Universiti Sains Malaysia (USM)40 enrolled1 locationACTRN12611000778987