Phase 1 Glucose Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Recruiting
Phase 1Phase 2

An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D

Diabetes MellitusMetabolic DiseaseDiabetes Mellitus, Type 1+4 more
CRISPR Therapeutics AG40 enrolled2 locationsNCT05565248
Completed
Phase 1

Comparative assessment of the absorption of a generic formulation of Inhaled Insulin against the innovators Humalog KwikPen for injection and the AFREZZA Inhalation Powder Cartridge conducted under fasting conditions in healthy male and female volunteers

Pharmacokinetic and pharmacodynamic study conducted in healthy volunteers comparing three formulations of Insulin with no health condition or problem studied. Insulin is a medicine that is used to lower blood glucose.
Zenith Technology Corp Ltd18 enrolled1 locationACTRN12615001100583
Recruiting
Phase 1

Effect of Fucoidan on glucose control and markers of cardiometabolic health after chronic dosing

Insulin Resistance/sensitivityHypercholesterolaemiaObesity+3 more
University of Tasmania.80 enrolled1 locationACTRN12614000495628
Completed
Phase 1

Does pulsatile administration of glucagon-like peptide-1 (GLP-1) when compared to continuous infusion have a greater effect on insulin secretion and blood glucose lowering in healthy humans?

Blood Glucose
Royal Adelaide Hospital Intensive Care Unit12 enrolled1 locationACTRN12612001040853
Recruiting
Phase 1

The effect of topical glucose on vitreous glucose concentration

Vitreous glucose concentration of the Eye
Robert Casson20 enrolled1 locationACTRN12611001225909
Completed
Phase 1

The effect of the glucagon-like peptide-1 analogue, exenatide, on duodenal motility and flow events, and small intestinal transit in healthy humans and type 2 diabetes mellitus.

Glucose absorptionSmall intestinal motility
Royal Adelaide Hospital24 enrolled1 locationACTRN12608000428369
Completed
Phase 1

Post-exercise Nutrition Recovery and Immune Response Study

Blood glucose and insulin and immune responses.
Dr Tracy Perry28 enrolled1 locationACTRN12605000168651