Phase 2 HD Clinical Trials

43 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 43 trials

Recruiting
Phase 2

Low-Dose ATG/PTCy Plus Ivarmacitinib for aGVHD Prevention in Haplo-PBSCT From Parous Female Donors

Graft-Versus-Host-Disease (GVHD)Bone Marrow Transplantation
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine82 enrolled1 locationNCT07570745
Recruiting
Phase 2

Evaluating Buspirone to Treat Opioid Withdrawal

AnxietyOpioid-use DisorderOpioid Withdrawal+1 more
University of Maryland, Baltimore100 enrolled1 locationNCT05511909
Recruiting
Phase 2

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Chronic PainDrug Dependence of Morphine TypeSymptom, Withdrawal
University of Calgary40 enrolled1 locationNCT04939623
Recruiting
Phase 1Phase 2

Prebiotic Galacto-oligosaccharide and Acute GVHD

Acute GVHD
University of Kansas Medical Center128 enrolled2 locationsNCT04373057
Recruiting
Phase 2

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

Chronic Graft-Versus-Host Disease (cGVHD)
H. Lee Moffitt Cancer Center and Research Institute120 enrolled5 locationsNCT06660355
Recruiting
Phase 2

Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention

Graft-Versus-Host-Disease (GVHD)allogeneic stem cell transplantationHematologic Malignancies
Milton S. Hershey Medical Center41 enrolled1 locationNCT06926595
Recruiting
Phase 2

Novel Therapies for Severe Acute GVHD (Graft-versus-host Disease)

GVHD,AcuteStem Cell Transplant Complications
Daihong Liu54 enrolled1 locationNCT07509749
Recruiting
Phase 2

A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

GvHDUndefinedGraft-Versus-Host Disease
Memorial Sloan Kettering Cancer Center44 enrolled9 locationsNCT05675930
Recruiting
Phase 2

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

Acute Myelogenous LeukemiaMyelodysplastic SyndromesAcute Lymphocytic Leukemia+1 more
Case Comprehensive Cancer Center36 enrolled1 locationNCT06904482
Recruiting
Phase 2

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal

Opioid UseOpiate Withdrawal Syndrome
University of Pennsylvania150 enrolled2 locationsNCT05995535
Recruiting
Phase 2

Clinical Trial to Investigate the Safety and Efficacy of Two Dexamfetamine Sulfate Formulations in Adults With ADHD and Moderate to Severe Depression

Depression - Major Depressive DisorderAttention Deficit Hyperactivity Disorder (ADHD)
Prof. Dr. Frank Behrens105 enrolled2 locationsNCT06967857
Recruiting
Phase 2

Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease )

GVHD,AcuteStem Cell Transplant Complications
Daihong Liu168 enrolled1 locationNCT07340723
Recruiting
Phase 2Phase 3

A Trial to Evaluate the Efficacy and Safety of EB-1020 in Pediatric Patients With ADHD

Attention Deficit Hyperactivity Disorder (ADHD)
Otsuka Pharmaceutical Co., Ltd.315 enrolled1 locationNCT07086313
Recruiting
Phase 2

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

Chronic Graft-Versus-Host Disease (cGVHD)
Deciphera Pharmaceuticals, LLC48 enrolled26 locationsNCT06619561
Recruiting
Phase 2

Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

Graft-Versus-Host-Disease (GVHD)Hematological Malignancies
University of Nebraska126 enrolled1 locationNCT06799195
Recruiting
Phase 2

Prazosin for Alcohol Use Disorder With Withdrawal Symptoms

alcohol withdrawal
Yale University150 enrolled2 locationsNCT04793685
Recruiting
Phase 2

BPC2001 for the Prevention of Acute Graft-Versus-Host Disease Following Haploidentical Stem Cell Transplantation

Graft-Versus-Host DiseaseaGVHDcGVHD+1 more
BioPhoenix Co., Ltd.50 enrolled1 locationNCT07246031
Recruiting
Phase 2

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease

Steroid Refractory GVHD
ReAlta Life Sciences, Inc.66 enrolled11 locationsNCT06343792
Recruiting
Phase 1Phase 2

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain

Chronic PainOpioid Withdrawal
Medical University of South Carolina240 enrolled1 locationNCT06442566
Recruiting
Phase 2

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

Acute LeukemiaGVHD,AcuteMyelodysplastic Syndromes+1 more
University of Alabama at Birmingham29 enrolled1 locationNCT06315309