Phase 2 HD Clinical Trials

46 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 46 trials

Recruiting
Phase 1Phase 2

Study to Evaluate the Safety and Effectiveness of Withaferin A as a Treatment to Prevent GvHD in Transplant Patients

Hematopoietic Stem Cell Transplant (HSCT)Hematological MalignancyGVHD - Graft-Versus-Host Disease
Tata Memorial Centre54 enrolled2 locationsNCT07724873
Recruiting
Phase 2

Study of Standardized Withaferin-A for the Treatment of Steroid Refractory Acute Graft Versus Host Disease.

Hematological MalignancyGVHD - Graft-Versus-Host DiseaseSteriod Refractory
Tata Memorial Centre34 enrolled1 locationNCT07708987
Recruiting
Phase 2

Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease

Chronic Graft Versus Host DiseasecGVHD
University of Miami49 enrolled3 locationsNCT06663722
Recruiting
Phase 2

A Study of Photobiomodulation (PBM) Therapy in People With Oral Graft-Versus-Host Disease (GVHD) After Stem Cell Transplant

GvHDUndefinedGraft-Versus-Host Disease
Memorial Sloan Kettering Cancer Center44 enrolled9 locationsNCT05675930
Recruiting
Phase 1Phase 2

Cannabigerol Oil for Adolescents With ADHD (CAN-ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)
Universidade do Sul de Santa Catarina60 enrolled1 locationNCT07592390
Recruiting
Phase 2

Low-Dose ATG/PTCy Plus Ivarmacitinib for aGVHD Prevention in Haplo-PBSCT From Parous Female Donors

Graft-Versus-Host-Disease (GVHD)Bone Marrow Transplantation
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine82 enrolled1 locationNCT07570745
Recruiting
Phase 2

Evaluating Buspirone to Treat Opioid Withdrawal

AnxietyOpioid-use DisorderOpioid Withdrawal+1 more
University of Maryland, Baltimore100 enrolled1 locationNCT05511909
Recruiting
Phase 2

Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal

Chronic PainDrug Dependence of Morphine TypeSymptom, Withdrawal
University of Calgary40 enrolled1 locationNCT04939623
Recruiting
Phase 1Phase 2

Prebiotic Galacto-oligosaccharide and Acute GVHD

Acute GVHD
University of Kansas Medical Center128 enrolled2 locationsNCT04373057
Recruiting
Phase 2

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

Chronic Graft-Versus-Host Disease (cGVHD)
H. Lee Moffitt Cancer Center and Research Institute120 enrolled5 locationsNCT06660355
Recruiting
Phase 2

Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention

Graft-Versus-Host-Disease (GVHD)allogeneic stem cell transplantationHematologic Malignancies
Milton S. Hershey Medical Center41 enrolled1 locationNCT06926595
Recruiting
Phase 2

Novel Therapies for Severe Acute GVHD (Graft-versus-host Disease)

GVHD,AcuteStem Cell Transplant Complications
Daihong Liu54 enrolled1 locationNCT07509749
Recruiting
Phase 2

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

Acute Myelogenous LeukemiaMyelodysplastic SyndromesAcute Lymphocytic Leukemia+1 more
Case Comprehensive Cancer Center36 enrolled1 locationNCT06904482
Recruiting
Phase 2

Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal

Opioid UseOpiate Withdrawal Syndrome
University of Pennsylvania150 enrolled2 locationsNCT05995535
Recruiting
Phase 2

Clinical Trial to Investigate the Safety and Efficacy of Two Dexamfetamine Sulfate Formulations in Adults With ADHD and Moderate to Severe Depression

Depression - Major Depressive DisorderAttention Deficit Hyperactivity Disorder (ADHD)
Prof. Dr. Frank Behrens105 enrolled2 locationsNCT06967857
Recruiting
Phase 2

Novel First-line Therapies for Grade II Acute GVHD(Graft-versus-host Disease )

GVHD,AcuteStem Cell Transplant Complications
Daihong Liu168 enrolled1 locationNCT07340723
Recruiting
Phase 2Phase 3

A Trial to Evaluate the Efficacy and Safety of EB-1020 in Pediatric Patients With ADHD

Attention Deficit Hyperactivity Disorder (ADHD)
Otsuka Pharmaceutical Co., Ltd.315 enrolled1 locationNCT07086313
Recruiting
Phase 2

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

Chronic Graft-Versus-Host Disease (cGVHD)
Deciphera Pharmaceuticals, LLC48 enrolled26 locationsNCT06619561
Recruiting
Phase 2

Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

Graft-Versus-Host-Disease (GVHD)Hematological Malignancies
University of Nebraska126 enrolled1 locationNCT06799195
Recruiting
Phase 2

Prazosin for Alcohol Use Disorder With Withdrawal Symptoms

alcohol withdrawal
Yale University150 enrolled2 locationsNCT04793685