Phase 2 Hearing Loss Clinical Trials
14 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–14 of 14 trials
Recruiting
Phase 1Phase 2
A Clinical Trial of EHT102 Injection in Pediatric Patients With Biallelic hOTOF Mutations
Treatment of Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
Shanghai Euhearing Therapeutics Co., Ltd30 enrolled1 locationNCT07288580
Recruiting
Phase 2
Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer
Head and Neck CancerHearing Loss
National Institute on Deafness and Other Communication Disorders (NIDCD)224 enrolled5 locationsNCT04915183
Recruiting
Phase 1Phase 2
Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss
Sensorineural Hearing Loss, Bilateral
Akouos, Inc.22 enrolled9 locationsNCT05821959
Recruiting
Phase 1Phase 2
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutations
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
Regeneron Pharmaceuticals30 enrolled15 locationsNCT05788536
Recruiting
Phase 1Phase 2
Intracochlear Application of VSF1.01 for the Reduction of Cochlear Implant Surgery Related Trauma
Hearing Loss
Hannover Medical School11 enrolled1 locationNCT06545175
Recruiting
Phase 2
Protective Effect of Acetylcysteine Against Cisplatinum-Induced Ototoxicity: A Randomized Controlled Trial
Sensorineural Hearing LossOtotoxicityOtotoxicity, Drug-Induced+1 more
Siriraj Hospital40 enrolled1 locationNCT07364747
Recruiting
Phase 2Phase 3
A Prospective, Open-label, Pivotal Study to Assess Spectacle Hearing Aid Safety and Efficacy
Hearing Loss Mixed
Nuance Hearing89 enrolled1 locationNCT07282028
Recruiting
Phase 2
SPI-1005 in Adults Receiving Cochlear Implant
Hearing LossCochlear Trauma
Sound Pharmaceuticals, Incorporated40 enrolled1 locationNCT06340633
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Trial with SENS-501 in Children Suffering from Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations
Hearing DisordersDeafnessHearing Loss, Sensorineural+5 more
Sensorion12 enrolled2 locationsNCT06370351
Recruiting
Phase 2
ACOU085 for Hearing Loss Prevention in Testicular Cancer Patients Receiving Cisplatin
Cisplatin-induced Hearing Loss
Acousia Therapeutics GmbH40 enrolled10 locationsNCT06521190
Recruiting
Phase 2
Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)
Hearing LossSmith-Lemli-Opitz SyndromeCone-Rod Dystrophy
University of Colorado, Denver100 enrolled1 locationNCT01773278
Recruiting
Phase 2
Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy
Ototoxic Hearing Loss
Sunnybrook Health Sciences Centre92 enrolled1 locationNCT05129748
Not Yet Recruiting
Phase 2
Phase 1b trial to investigate the prevention of hearing loss in cancer patients receiving cisplatin chemotherapy
Hearing loss (ototoxicity from cisplatin medication)
Decibel Therapeutics Australia Pty Ltd70 enrolled5 locationsACTRN12620000182998
Withdrawn
Phase 2Phase 3
Randomised controlled trial comparing conventional steroid treatment to conventional steroids plus hyperbaric oxygen treatment in sudden sensorineural hearing loss within two weeks of onset.
Sudden idiopathic sensorineural hearing loss
University of Queensland100 enrolled6 locationsACTRN12619001495112