Heart Disease Clinical Trials in London

17 recruitingLondon, United Kingdom

Showing 117 of 17 trials

Recruiting
Phase 2

Transition to KPL-387 Monotherapy Dosing & Administration Study

PericarditisHeart DiseasesRecurrent Pericarditis
Kiniksa Pharmaceuticals International, plc80 enrolled32 locationsNCT07288216
Recruiting
Not Applicable

CTCA Prior to Invasive Angiography in Post-Bypass Patients (BYPASS CTCA 2)

Coronary Heart Disease
Queen Mary University of London1,000 enrolled1 locationNCT07165678
Recruiting
Phase 1

A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

Premature Coronary Heart DiseaseHeterozygous Familial Hypercholesterolemia
Verve Therapeutics, Inc.85 enrolled23 locationsNCT06164730
Recruiting
Phase 3

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company587 enrolled101 locationsNCT06563895
Recruiting

Abbott Structural Heart Device Registry

Heart DiseasesValvular Heart DiseasePFO - Patent Foramen Ovale+3 more
Abbott Medical Devices2,500 enrolled28 locationsNCT06590467
Recruiting
Not Applicable

iCorMicA - Stratified Medicine in Angina

Coronary Artery DiseaseCoronary Microvascular Dysfunction (CMD)Angina, Stable+7 more
NHS Greater Glasgow and Clyde1,500 enrolled39 locationsNCT04674449
Recruiting
Not Applicable

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

Heart DiseasesCoronary Artery DiseaseCoronary Artery Bypass Grafting
Weill Medical College of Cornell University2,300 enrolled146 locationsNCT04124120
Recruiting

Prospective Evaluation of AI-ECG for SHD Detection

Heart Failure With Preserved Ejection Fraction (HFpEF; Diagnosis)Valvular Heart Disease Stenosis and Regurgitation (Diagnosis)Pulmonary Hypertension (Diagnosis)+1 more
Imperial College London590 enrolled5 locationsNCT07057466
Recruiting

Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry

Congenital Heart DiseaseAdult Congenital Heart DiseaseSystemic Right Ventricle+5 more
Leiden University Medical Center400 enrolled11 locationsNCT06932081
Recruiting
Not Applicable

Can Tiny Bubbles Offer an Alternative to Catheters for Assessing Pressures Inside the Heart? Investigating Ultrasound Contrast Agents as Pressure Sensors Against Gold Standard Catheter Pressures in Cardiac Catheterisation Patients.

Heart DiseaseHFpEF - Heart Failure With Preserved Ejection FractionCardiac Catheterisation
King's College London10 enrolled1 locationNCT07416279
Recruiting
Not Applicable

A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

Arterial Occlusive DiseasesCardiovascular DiseasesMyocardial Ischemia+4 more
Fundación EPIC700 enrolled13 locationsNCT07286578
Recruiting
Not Applicable

ISCHEMIA-CTO Trial - Revascularisation or Optimal Medical Therapy of CTO

Ischemic Heart DiseaseChronic Total Occlusion of Coronary Artery
Aarhus University Hospital Skejby1,560 enrolled27 locationsNCT03563417
Recruiting
Not Applicable

Personalized Responses to Dietary Composition Trial 3

ObesityHealthyDiabetes+5 more
Zoe Global Limited250,000 enrolled2 locationsNCT04735835
Recruiting
Not Applicable

Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4)

Cardiovascular DiseasesValvular Heart DiseaseSurgery--Complications+1 more
University of Leicester100 enrolled11 locationsNCT05996120
Recruiting

Predicting the Risk of Non-culprit Coronary Artery Disease After a Heart Attack

Coronary Artery DiseaseIschemic Heart DiseaseST Elevation Myocardial Infarction
Guy's and St Thomas' NHS Foundation Trust90 enrolled2 locationsNCT05781087
Recruiting
Not Applicable

Therapy to Maintain Remission in Dilated Cardiomyopathy

Heart FailureCardiomyopathiesHeart Diseases+1 more
Imperial College London50 enrolled1 locationNCT06091475
Recruiting

Cardiometabolic Health in First Time Pregnancy

Cardiometabolic healthDiabetesHeart Diseases+2 more
Cambridge University Hospitals NHS Foundation Trust3,500 enrolled7 locationsNCT05856318