Therapy to Maintain Remission in Dilated Cardiomyopathy

This study is testing whether people with dilated cardiomyopathy — a condition where the heart muscle becomes weakened and enlarged — can safely reduce or stop their heart medications once their heart has recovered to normal function. **You may be eligible if...** - You have been diagnosed with dilated cardiomyopathy - Your heart function was once below 40% but has now recovered to above 50% - Your heart size is back to normal on imaging - Your heart failure blood marker (NT-pro-BNP) is low (below 250 ng/L) - You have no symptoms of heart failure (NYHA Class I) - You are in normal heart rhythm (sinus rhythm) - You are currently taking heart failure medications including a beta-blocker and either an ACE inhibitor, ARB, or sacubitril-valsartan, plus a water pill (MRA) or SGLT2 inhibitor **You may NOT be eligible if...** - You have atrial fibrillation (irregular heartbeat) - You have had dangerous heart rhythm problems (ventricular tachycardia or fibrillation) - You have certain genetic heart conditions (LMNA, DSP, FLNC, or RBM20 gene variants) - A close family member died suddenly of heart disease under age 50 - You have kidney disease (eGFR below 60) or are planning a pregnancy - You have active heart inflammation - You have diabetes managed with an SGLT2 inhibitor Talk to your doctor to see if this trial is right for you.