Phase 3 Heart Disease Clinical Trials
12 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–12 of 12 trials
Recruiting
Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
CardiomyopathiesAmyloidosisHeart Diseases+3 more
Eidos Therapeutics, a BridgeBio company582 enrolled98 locationsNCT06563895
Recruiting
Phase 2Phase 3
Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT)
Pulmonary HypertensionRheumatic Valvular Heart Disease
Sindh Institute of Cardiovascular Diseases100 enrolled1 locationNCT07462260
Recruiting
Phase 3
Lumason® Infusion vs. Bolus Administrations
Heart Diseases
Bracco Diagnostics, Inc106 enrolled6 locationsNCT06400004
Recruiting
Phase 3
Fontan Udenafil Exercise Longitudinal Assessment Trial - 2
Single Ventricle Heart Disease
Mezzion Pharma Co. Ltd436 enrolled40 locationsNCT05918211
Recruiting
Phase 3
Effect of Sacubitril-Valsartan on Cardiac Structure and Function
Congenital Heart Disease
Mayo Clinic45 enrolled1 locationNCT06693674
Recruiting
Phase 3
NO During CPB in Neonates to Reduce Risk of AKI
SurgeryAKICHD - Congenital Heart Disease
Children's Hospital Medical Center, Cincinnati40 enrolled1 locationNCT04216927
Recruiting
Phase 2Phase 3
Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
HypoxiaNeurodevelopmental DisordersCongenital Heart Disease in Children+1 more
University of Utah150 enrolled5 locationsNCT05767385
Recruiting
Phase 3
Efficacy and Safety of Colchicine After PCI
Coronary Heart DiseasePercutaneous Coronary InterventionColchicine
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology8,862 enrolled36 locationsNCT06472908
Recruiting
Phase 3
Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary Bypass
Congenital Heart Disease in ChildrenNeuroprotection
dr. M.J.N.L. Benders236 enrolled4 locationsNCT04217421
Completed
Phase 3Phase 4
Fiji Northern Division Ivermectin Mass Drug Administration for Scabies Trial
Post streptococcal glomerulonephritisInvasive group A streptococcal infectionsSkin and soft tissue infections+3 more
Murdoch Children's Research Insititute135,000 enrolled1 locationACTRN12618000461291
Recruiting
Phase 3
The effect of Colchicine on Cardiovascular Outcomes in Acute Coronary Syndrome Study (The COLCARDIO-ACS Study)
AtherosclerosisIschaemic heart disease
University of Sydney3,000 enrolled16 locationsACTRN12616000400460
Completed
Phase 3
The Australian COPS trial - COlchicine in Patients with acute coronary Syndromes
Ischaemic heart disease
St. Vincent's Hospital Melbourne1,009 enrolled1 locationACTRN12615000861550