Phase 2 Hematopoietic Stem Cell Transplantation Clinical Trials

12 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 112 of 12 trials

Recruiting
Phase 2

A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Hematopoietic Stem Cell TransplantationImmunodeficiency
National Cancer Institute (NCI)54 enrolled1 locationNCT05027945
Recruiting
Phase 2

Moxibustion for Steroid-Refractory Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Acute Graft Versus Host DiseaseGraft-Versus-Host DiseaseALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology42 enrolled1 locationNCT07572669
Recruiting
Phase 1Phase 2

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell TransplantationPeripheral Blood Stem Cell Transplantation
National Cancer Institute (NCI)260 enrolled2 locationsNCT05436418
Recruiting
Phase 2

Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients

Oral MucositisHematopoietic Stem Cell TransplantationStomatitis+1 more
The First Affiliated Hospital of Soochow University22 enrolled1 locationNCT07400328
Recruiting
Phase 2

Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation

allogeneic stem cell transplantationHematologic MalignanciesALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION
University of California, Irvine60 enrolled1 locationNCT06028828
Recruiting
Phase 2

Inotuzumab Ozogamicin in the Treatment of MRD+ After HSCT of ALL

ALLMRD-positiveHematopoietic Stem Cell Transplantation
Sheng-Li Xue, MD42 enrolled1 locationNCT05940961
Recruiting
Phase 2

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Acute Lymphoblastic LeukemiaAcute LeukemiaMyeloproliferative Neoplasm+14 more
Fred Hutchinson Cancer Center68 enrolled10 locationsNCT03779854
Recruiting
Phase 2

Phase 2 Trial of BN104 as Post-HSCT Maintenance in Acute Leukemia

Acute LeukemiaMenin InhibitorsPost Hematopoietic Stem Cell Transplantation+4 more
The First Affiliated Hospital of Soochow University60 enrolled1 locationNCT07101497
Recruiting
Phase 2

Demethylating Agents Combined With Venetoclax for High-risk T-cell Lymphoblastic Lymphoma/Leukemia Post-Transplant Relapse Prevention

RelapseT-cell Acute Lymphoblastic LeukemiaALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine59 enrolled1 locationNCT06686108
Recruiting
Phase 2

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

Hematopoietic Stem Cell TransplantationThrombotic Microangiopathies
Omeros Corporation18 enrolled16 locationsNCT05855083
Recruiting
Phase 2

Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide in Patients With Acquired Refractory Aplastic Anemia or in Relapse After Immunosuppression

Refractory Idiopathic Aplastic AnemiaHaploidentical Allogeneic Hematopoietic Stem Cell Transplantation
Assistance Publique - Hôpitaux de Paris31 enrolled35 locationsNCT05126849
Recruiting
Phase 2

An open label, study to evaluate the safety of Cannabidiol (CBD) for the prevention of Acute Graft-Versus-Host Disease (GVHD) after allogeneic hematopoietic cell transplantation.

Acute Graft Versus Host DiseaseHematopoietic Stem Cell Transplantation
Kalytera Therapeutics Israel Ltd36 enrolled2 locationsACTRN12619000623190