Phase 3 Hematopoietic Clinical Trials

15 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 115 of 15 trials

Recruiting
Phase 3

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm
Children's Oncology Group105 enrolled29 locationsNCT05711667
Recruiting
Phase 3

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

Hematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasm
Children's Oncology Group60 enrolled193 locationsNCT06513962
Recruiting
Phase 3

Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Cancer Treatment

Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm
University of Rochester NCORP Research Base400 enrolled153 locationsNCT04829539
Recruiting
Phase 3

MRD-guided Maintenance Post-HCT: Gilteritini vs Sorafenib

Acute Myeloid Leukemia (AML)Maintenance TherapyAllogeneic Hematopoietic Cell Transplantation (HCT)+3 more
The First Affiliated Hospital of Soochow University594 enrolled2 locationsNCT07463651
Recruiting
Phase 3

Fludarabine Plus Melphalan Versus Addition of Venetoclax to Fludarabine/Melphalan Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in AML/MDS Patients Aged > 50 Years: a Multicenter, Randomized, Phase 3 Trial

VenentoclaxALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATIONMyeloid Malignancies+3 more
First Affiliated Hospital of Zhejiang University186 enrolled18 locationsNCT07396480
Recruiting
Phase 3

Study Comparing Reduced Versus Standard Dose Post-transplantation Cyclophosphamide in Combination With Post-engraftment Anti-thymoglobin as Graft Versus Host Disease Prophylaxis in Alternative Donor Peripheral Stem Cell Transplantation

Allogeneic Hematopoietic Cell TransplantGraft-Versus-Host Disease
Shanghai Jiao Tong University School of Medicine316 enrolled1 locationNCT06705062
Recruiting
Phase 3

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

AnorexiaHematopoietic and Lymphoid Cell NeoplasmAdvanced Malignant Solid Neoplasm
Alliance for Clinical Trials in Oncology360 enrolled293 locationsNCT04939090
Recruiting
Phase 3

Comparison of Etamsylate Versus Placebo to Prevent Bleeding in HSCT

ThrombocytopeniaHematopoietic Stem Cell Transplantation
First Affiliated Hospital of Zhejiang University404 enrolled1 locationNCT07442513
Recruiting
Phase 3

CD19 CAR-T vs DLI for Post-HSCT MRD in Ph- ALL: A RCT

B-ALLMRD-positiveAllogenetic Hematopoietic Stem Cell Transplantation
Peking University People's Hospital70 enrolled1 locationNCT07441291
Recruiting
Phase 3

A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy

Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD)Solid Organ Transplant ComplicationsLymphoproliferative Disorders+2 more
Pierre Fabre Medicament115 enrolled71 locationsNCT03394365
Recruiting
Phase 3

Comparison Study of EAP and Disease-Specific Chemotherapy Regimens in Hematopoietic Stem Cell Mobilization for Lymphoma

Non-Hodgkin's LymphomaHematopoietic Stem Cell Mobilization
The Affiliated People's Hospital of Ningbo University99 enrolled17 locationsNCT06520163
Recruiting
Phase 3

Comparison Study of EAP and CG Regimens for Mobilizing Hematopoietic Stem Cells in Multiple Myeloma Patients

Multiple MyelomaHematopoietic Stem Cell Mobilization
The Affiliated People's Hospital of Ningbo University99 enrolled16 locationsNCT06520176
Recruiting
Phase 3

Haplo-cord HCT vs. Haplo-HCT for T-ALL Patients

Acute T Cell Lymphoblastic LeukemiaHaploidentical Hematopoietic Stem Cell TransplantationCord Blood
The First Affiliated Hospital of Soochow University146 enrolled1 locationNCT06381817
Recruiting
Phase 3

Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic HSCT

Hematopoietic Stem Cell TransplantationStomatitisLow-Level Light Therapy
Instituto Nacional de Cancer, Brazil84 enrolled2 locationsNCT06071637
Withdrawn
Phase 3

A Phase III Study Comparing Low Dose Cyclosporine, Methotrexate And Prednisone Versus Standard Dose Cyclosporine and Methotrexate As Graft Versus Host Disease Prophylaxis In Myeloblative Allogeneic Stem Cell Transplantation (ALLG BM10 trial). (Incorporating an Open-Label Sub-study Investigating The Use Of Valganciclovir In The Prevention Of Cytomegalovirus Infection In Hematopoietic Stem Cell Transplant Recipients (ML20712))

Prevention Of CytomegalovirusCell Transplant RecipientsProphylaxis In Myeloblative+3 more
Australasian Leukaemia and Lymphoma Group300 enrolled1 locationACTRN12607000347460