Phase 1 Hemophilia A Clinical Trials
8 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–8 of 8 trials
Recruiting
Phase 1Phase 2
A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
Hemophilia A
Hoffmann-La Roche5 enrolled2 locationsNCT07226206
Recruiting
Phase 1
Lentiviral FVIII Gene Therapy
Hemophilia A
Shenzhen Geno-Immune Medical Institute10 enrolled1 locationNCT03217032
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A
Hemophilia A
Hoffmann-La Roche60 enrolled14 locationsNCT05987449
Recruiting
Phase 1
A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.
Severe Hemophilia A
Pfizer15 enrolled4 locationsNCT06703606
Recruiting
Phase 1
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)
Healthy ParticipantsHemophilia AHemophilia B+1 more
Equilibra Bioscience LLC31 enrolled10 locationsNCT06349473
Recruiting
Phase 1
Pharmacokinetic Comparison of Efanesoctocog Alfa vs Other EHL-rFVIII Products in Participants With Severe Haemophilia A
Hemophilia A
Swedish Orphan Biovitrum24 enrolled8 locationsNCT06579144
Recruiting
Phase 1Phase 2
ASC618 Gene Therapy in Hemophilia A Patients
Hemophilia A
ASC Therapeutics12 enrolled1 locationNCT04676048
Completed
Phase 1
Understanding the blood level of a new coagulant factor VIIa in participants with congenital Haemophilia A
Congenital Hemophilia A in subjects with or without Inhibitors to Factor VIII
LFB USA, Inc.28 enrolled3 locationsACTRN12620001152910