Early Phase 1 HER2 Clinical Trials

7 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 17 of 7 trials

Recruiting
Early Phase 1

Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

Metastatic CancerHER2Locally Advanced Cancer+2 more
Vanderbilt-Ingram Cancer Center30 enrolled1 locationNCT06828588
Recruiting
Early Phase 1

SPH5030 Tablets in Subjects With Advanced Her2-positive Solid Tumors

HER2-Positive Advanced Solid Tumors
Shanghai Pharmaceuticals Holding Co., Ltd150 enrolled17 locationsNCT05245058
Recruiting
Early Phase 1

HEAT Trial (HER2 Antibody Therapy With Lutetium-177)

Advanced Solid TumorsHER2 Gene Mutation
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06824155
Recruiting
Early Phase 1

Neoadjuvant Therapy and Contrast-enhanced Mammography for Early Stage Breast Cancer

Breast CancerTriple-Negative Breast CancerHER2-positive Breast Cancer+3 more
Alison Stopeck30 enrolled1 locationNCT06220214
Recruiting
Early Phase 1

TGW211 for Click-Cleavable Imaging in HER2-Positive Cancers.

HER2-Positive Solid Tumor
Radboud University Medical Center19 enrolled1 locationNCT07009184
Recruiting
Early Phase 1

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

HER2-Negative Breast CarcinomaAnatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+3 more
Emory University40 enrolled4 locationsNCT05464810
Recruiting
Early Phase 1

Dual-targeting HER2 and PD-L1 CAR-T for Solid Tumors

Pleural Effusion, MalignantPeritoneal Carcinoma MetastaticHER2 Positive Malignancies
Sichuan University18 enrolled1 locationNCT04684459