Phase 1 HIT Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1Phase 2
An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease
Vanishing White Matter Disease
Calico Life Sciences LLC50 enrolled5 locationsNCT05757141
Recruiting
Phase 1Phase 2
Retina is a Marker for Cerebrovascular Heath
Cerebral Small Vessel DiseasesCerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and LeukoencephalopathyCerebral Microbleeding+1 more
Mayo Clinic100 enrolled1 locationNCT04753970
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies
Chronic Lymphocytic Leukemia (CLL)High Grade B-Cell Lymphoma, Not Otherwise SpecifiedMultiple Myeloma (MM)+3 more
IDP Discovery Pharma S.L.37 enrolled11 locationsNCT05908409
Not Yet Recruiting
Phase 1
Probiotic dietary supplement and stool evaluation to improve ileal pouch health
Pouchitis
University of Otago20 enrolled1 locationACTRN12613000544774
Completed
Phase 1
A study of aerosol Amikacin and Fosfomycin delivered via a new nebulizer system in mechanically ventilated patients.
Ventilator Associated Tracheobronchitis (VAT)
Cardeas Pharma9 enrolled1 locationACTRN12612000273886
Not Yet Recruiting
Phase 1
Pharmacokinetics and Safety of Solid Oral Posaconazole(SCH 56592) in Subjects at High Risk for Invasive Fungal Infections
High Risk for Invasive Fungal Infection due to:
- Hematopoietic stem cell transplant (HSCT) recipients undergoing treatment for graft-versus-host disease (GVHD)High Risk for Invasive Fungal Infection due to:
- Expected neutropenia (low white blood cell count) due to chemotherapy for Acute Myelogenous Leukaemia (AML) or Myelodysplastic Syndrome (MDS)
Schering-Plough Pty limited160 enrolled1 locationACTRN12611000364976
Completed
Phase 1
Immunogenicity and safety of orally administered killed whole cell non-typeable Haemophilus influenzae (Study HI-H003)
Smokers at risk of recurrent bronchitis
The University of Newcastle Research Associates (TUNRA) Ltd64 enrolled1 locationACTRN12607000271404