Phase 1 HRD Clinical Trials

3 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–3 of 3 trials

Recruiting

Phase 1

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

Advanced Malignancies With Homologous Recombination Deficiency (HRD) (Breast, Ovarian, mCRPC, Brain Metastases)

Duke Street Bio Ltd180 enrolled15 locationsNCT06458712

Recruiting

Phase 1Phase 2

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

Advanced Solid TumorsSCLCHRD Cancer

National Cancer Institute (NCI)120 enrolled1 locationNCT04826341

Recruiting

Phase 1

Study of SYN818 With Olaparib for the Treatment of Locally Advanced or Metastatic Solid Tumors

Breast CancerOvarian CancerMetastatic Solid Tumor+2 more

Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd110 enrolled2 locationsNCT07156253