Phase 1 Idiopathic Pulmonary Fibrosis Clinical Trials
17 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–17 of 17 trials
Recruiting
Phase 1
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of MNKD-201 in Patients With Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis (IPF)
Mannkind Corporation24 enrolled8 locationsNCT07344558
Recruiting
Phase 1
NAL ER IPF Respiratory Function and Safety Study
Idiopathic Pulmonary Fibrosis
Trevi Therapeutics10 enrolled2 locationsNCT07036029
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SRN001 in Healthy Korean and Caucasian Adult Males
Idiopathic Pulmonary Fibrosis
siRNAgen Therapeutics Inc.30 enrolled1 locationNCT07407543
Recruiting
Phase 1Phase 2
Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure
Idiopathic Pulmonary FibrosisEmphysema or COPD
Paul Szabolcs8 enrolled2 locationsNCT03500731
Recruiting
Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
Idiopathic Pulmonary Fibrosis
Joseph C. Wu15 enrolled1 locationNCT05988463
Recruiting
Phase 1
A Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GNS-3545 in Healthy Participants
Idiopathic Pulmonary Fibrosis
Genosco Inc.72 enrolled1 locationNCT07225296
Recruiting
Phase 1
Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
University of Alabama at Birmingham10 enrolled1 locationNCT04362644
Recruiting
Phase 1
A Trial of HRS-9813 in Healthy Subjects
Idiopathic Pulmonary Fibrosis/Progressive Pulmonary Fibrosis
Guangdong Hengrui Pharmaceutical Co., Ltd60 enrolled1 locationNCT06821464
Recruiting
Phase 1
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for IPF
Idiopathic Pulmonary Fibrosis
The Foundation for Orthopaedics and Regenerative Medicine20 enrolled1 locationNCT05016817
Completed
Phase 1
A Phase 1 Study of AP02 (Nintedanib Solution for Inhalation) Delivered via the PARI eFlow® Nebulizer System to Evaluate the Safety, Tolerability, and Pharmacokinetics of AP02 in Healthy Volunteers (AP02-002)
Idiopathic Pulmonary Fibrosis
Avalyn Pharma, Inc.68 enrolled1 locationACTRN12624000825550
Recruiting
Phase 1
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of RSN0402 in Healthy Volunteers
Idiopathic Pulmonary FibrosisLung; Disease, Interstitial, With Fibrosis
Shenzhen Resproly Biopharmaceutical Co., Ltd72 enrolled3 locationsNCT06482190
Recruiting
Phase 1
Safety, Tolerability and Efficacy of VUM02 Injection in Treatment of Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic Pulmonary Fibrosis
Wuhan Optics Valley Vcanbiopharma Co., Ltd.9 enrolled4 locationsNCT06230822
Completed
Phase 1
A Phase 1 Study of AP02 (Nintedanib Solution for Inhalation) Delivered via the PARI eFlow® Nebulizer System in Healthy Volunteers and Patients with Idiopathic Pulmonary Fibrosis or Progressive Fibrosing Interstitial Lung Disease
Progressive, Fibrosing Interstitial Lung DiseasesIdiopathic Pulmonary Fibrosis
Avalyn Pharma Pty Ltd38 enrolled1 locationACTRN12620001141932
Completed
Phase 1
Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetic Properties of DWN12088 following Oral Administration in Healthy Volunteers
Idiopathic Pulmonary Fibrosis (IPF)
Daewoong Pharmaceutical Co., Ltd.80 enrolled1 locationACTRN12619001239156
Completed
Phase 1
A Randomized Open-Label, Phase 1b Study of the Safety of Pirfenidone Solution for Inhalation (AP01) in Patients with Idiopathic Pulmonary Fibrosis (ATLAS Study)
Idiopathic Pulmonary Fibrosis
Avalyn Pharma Pty Ltd100 enrolled17 locationsACTRN12618001838202
Completed
Phase 1
A Single Ascending Dose and Multiple Ascending Dose Phase I Study of PXS-5382A Administered Orally
Idiopathic Pulmonary FibrosisLiver Fibrosis
Pharmaxis72 enrolled2 locationsACTRN12617001564347
Completed
Phase 1
A Study of Pirfenidone Solution for Inhalation in Healthy Volunteers, Smokers or Former Smokers with Decreased Lung function, and Patients with Idiopathic Pulmonary Fibrosis (IPF) to determine pharmacokinetics, as well as the safety and tolerability in volunteers with a history of smoking with decreased lung function and IPF patients.
Idiopathic Pulmonary Fibrosis
Avalyn Pharma Pty Ltd44 enrolled1 locationACTRN12617001501336