Phase 2 Immune Checkpoint Inhibitor Clinical Trials
12 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–12 of 12 trials
Recruiting
Phase 2
Thymosin Alpha 1 Combined With Anti-PD-1 Monoclonal Antibody in Elderly Patients With Advanced Melanoma
MelanomaImmune Checkpoint InhibitorImmune-related Adverse Event
Sun Yat-sen University55 enrolled2 locationsNCT07644897
Recruiting
Phase 2
Spatially Fractionated Radiotherapy Combined With Immunotherapy for Advanced Solid Tumors
Lung CancerRadiotherapyImmune Checkpoint Inhibitor+1 more
Tianjin Medical University Cancer Institute and Hospital30 enrolled3 locationsNCT07058948
Recruiting
Phase 2
Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction
Stomach NeoplasmsImmune Checkpoint Inhibitors
Xijing Hospital116 enrolled5 locationsNCT06576921
Recruiting
Phase 2
ctDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immunotherapy (CR1STAL-Adaptive)
Non-small Cell Lung CancerImmune Checkpoint Inhibitors (ICIs)
Second Xiangya Hospital of Central South University70 enrolled20 locationsNCT06951646
Recruiting
Phase 2
Early Vedolizumab as First-Line for Immune-Related Colitis Therapy Trial
Immune Checkpoint Inhibitor-Related Colitis
Shilpa Grover, MD, MPH80 enrolled2 locationsNCT06841705
Recruiting
Phase 2
JAK Inhibitors for Solid Malignant Tumor Patients With Immune Checkpoint Inhibitors-related Dermatitis: A Open-lable, Single Arm, Phase IIa Trial
Immune Checkpoint Inhibitors (ICI)-Related Dermatitis
Shixiu Wu35 enrolled1 locationNCT06715982
Recruiting
Phase 2
A Study of Multimodal Radiotherapy for Renal Cell Carcinoma Progressed After Prior Immunotherapy
Renal Cell CarcinomaRadiotherapyImmune Checkpoint Inhibitor
Jinling Hospital, China35 enrolled1 locationNCT06255223
Recruiting
Phase 2Phase 3
Electroacupuncture Combined With Immune Checkpoint Inhibitors as Adjuvant Therapy After Surgery for Early-stage Non-small Cell Lung Cancer
Non-small Cell Lung CancerElectroacupunctureImmune Checkpoint Inhibitors
Kong Fanming405 enrolled1 locationNCT07034326
Recruiting
Phase 2
Fruquintinib After ICIs Treatment in Unresectable Hepatocellular Carcinoma
Hepatocellular CarcinomaImmune Checkpoint InhibitorsSecond-line Treatment+1 more
Sun Yat-sen University36 enrolled1 locationNCT06446154
Recruiting
Phase 2
Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma (ESCC)Neoantigen-loaded Dendritic Cell VaccineImmune Checkpoint Inhibitors (ICIs)
Sichuan University165 enrolled1 locationNCT06675201
Recruiting
Phase 2
Toripalimab Plus FLOT in Locally Advanced Gastric Cancer
ChemotherapyLocally Advanced Gastric CarcinomaImmune Checkpoint Inhibitor
Henan Cancer Hospital60 enrolled1 locationNCT04891016
Recruiting
Phase 2
PD-1 Antibody Plus Chemoradiotherapy for IB2-IIIB Cervical Cancer
Cervical CarcinomaImmunotherapyImmune Checkpoint Inhibitor+6 more
Lei Li92 enrolled1 locationNCT05311566