Phase 3 Infants Clinical Trials
21 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 21 trials
Recruiting
Phase 3
Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome
Respiratory distress syndromePre-term Infants
Aerogen Pharma Limited520 enrolled12 locationsNCT06776783
Not Yet Recruiting
Phase 3
Resuscitation of term or near term infants at birth with air or 100% oxygen (Resair 3) A Randomised Controlled Trial
Resuscitation of depressed term or near term infants at birth
University of Queensland240,000 enrolled9 locationsACTRN12625001364460
Recruiting
Phase 2Phase 3
BabySTrong II taVNS Feeding Trial
Feeding DelaysNeonates and Term Infants
Medical University of South Carolina88 enrolled1 locationNCT07049952
Recruiting
Phase 3
Phase 3 Infant Safety & Immunogenicity Trial of MVA-BN® in DRC
SafetyVaccinationChildren+3 more
Jean-Pierre Van geertruyden344 enrolled1 locationNCT06844487
Recruiting
Phase 3
Combined Immuno-chemotherapy for Patients With B-linear Acute Lymphoblastic Leukemia Diagnosed From 0 to 365 Days of Life (ALL-Baby-2021)
Acute Lymphoblastic Leukemia, PediatricALL, Infants
Federal Research Institute of Pediatric Hematology, Oncology and Immunology80 enrolled1 locationNCT05029531
Recruiting
Phase 3
Reducing operative birth for fetal distress in women with small or suboptimally grown infants - The RidStress 2 Randomised Controlled Trial
Small for gestational age infantsOperative birth (caesarean or instrumental birth)Birth asphyxia
Mater Misericordiae Ltd660 enrolled4 locationsACTRN12621000354886
Active
Phase 3
Targeted Oxygenation in the Respiratory care of Premature Infants at Delivery: Effects on Outcome (TORPIDO 30/60)
Premature infants requiring resuscitation at birth
University of Sydney1,470 enrolled13 locationsACTRN12618000879268
Recruiting
Phase 3
Intravenous pentoxifylline as adjunct therapy to improve long-term disability in preterm infants
Late-onset sepsis (LOS)Preterm infantsNecrotising enterocolitis (NEC)+1 more
University of Sydney1,800 enrolled25 locationsACTRN12616000405415
Suspended
Phase 2Phase 3
The Torpido2 Study: Targeted Oxygenation in the Respiratory care of Premature Infants at Delivery: Effects on developmental Outcome
Oxidative stress in premature infantsBronchopulmonary dysplasia in premature infantsResuscitation of premature infants+2 more
University of Sydney1,200 enrolled5 locationsACTRN12615000115538
Recruiting
Phase 2Phase 3
The To2rpido Study: Targeted Oxygenation in the Resuscitation of Premature Infants and their Developmental Outcome
Oxidative stress in premature infantsBronchopulmonary dysplasia in premature infantsResuscitation in premature infants+1 more
The Royal Hospital for Women1,892 enrolled1 locationACTRN12610001059055
Recruiting
Phase 3Phase 4
A randomised controlled trial of pneumococcal conjugate vaccines Synflorix and Prevenar13 in sequence or alone in high-risk Indigenous infants (PREV-IX): immunogenicity, carriage and otitis media outcomes
Non-typeable Haemophilus influenzae diseaseOtitis media in Indigenous infantsPneumococcal disease
Menzies School of Health Research425 enrolled1 locationACTRN12610000544077
Completed
Phase 3
Randomised trial of dopamine vs dobutamine for treatment of low systemic blood flow in very preterm infants
Low systemic blood flow in preterm infants
A/Prof Nick Evans45 enrolled1 locationACTRN12607000152426
Recruiting
Phase 3
The use of probiotics to reduce the incidence of sepsis in premature infants.
Late onset sepsis in very premature infants (<32 weeks)
The Royal Women's Foundation Ltd1,100 enrolled1 locationACTRN12607000144415
Terminated
Phase 3
BOOST II: Benefits Of Oxygen Saturation Targeting Study
Preterm infants
NHMRC Clinical Trials Centre1,200 enrolled1 locationACTRN12605000055606
Completed
Phase 3
Transfer of preterm infants from incubator to open cot at a lower body weight (1600g) versus a higher body weight (1800g)
Premature infants
Division of neonatology, Royal Brisbane & Women's Hospital180 enrolled1 locationACTRN12606000518561
Completed
Phase 3
The DINO Trial
Preterm Infants < or = 32 weeks
National Health and Medical Research Council640 enrolled1 locationACTRN12606000327583
Completed
Phase 3
Skin exposure during conventional phototherapy in preterm infants: A Randomised Controlled Trial
Preterm infants with physiological jaundice
The University of Queensland60 enrolled1 locationACTRN12606000474550
Completed
Phase 3
International neonatal immunotherapy study
Infants with sepsis. Infants being treated with antibiotics are eligible. Infants can be preterm or term.
The University of Sydney5,000 enrolled1 locationACTRN12606000273583
Recruiting
Phase 3
A trial to determine if cooling newborn infants at risk of brain damage improves outcome
Term infants with hypoxic ischaemic encephalopathy
Murdoch Children's Research Institute300 enrolled1 locationACTRN12606000036516
Completed
Phase 3
Australasian Collaborative Trial of Magnesium Sulphate for the Prevention of Mortality and Cerebral Palsy in Infants Born Very Preterm.
Infants born very preterm (<30 weeks)
Prof Caroline Crowther1,178 enrolled1 locationACTRN12606000252516