Phase 4 Inflammatory Clinical Trials
24 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 24 trials
Recruiting
Phase 4
Taper Or Abrupt Steroid Stop: TOASSTtrial
AutoimmuneInflammatory Disorder
University Hospital, Basel, Switzerland530 enrolled16 locationsNCT03153527
Recruiting
Phase 4
Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases
Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912
Recruiting
Phase 4
Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE
Cardiovascular DiseasesInflammatory ResponseAcute Myocardial Infarction
Region Örebro County90 enrolled3 locationsNCT06336317
Recruiting
Phase 4
Two Dose Levels of Privigen in Pediatric CIDP
Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
CSL Behring30 enrolled9 locationsNCT03684018
Not Yet Recruiting
Phase 4
Upadacitinib versus Oral Corticosteroid for Induction of Transmural Remission in Moderate to Severe Ulcerative Colitis and Crohn’s Disease Flares - INDUCE
Crohn's DiseaseUlcerative ColitisInflammatory Bowel Disease
Mater Misericordiae Ltd80 enrolled1 locationACTRN12625000861459
Recruiting
Phase 4
Immunoinflammatory Regulation of Esketamine in Septic Patients
SepsisInflammatory ResponseEsketamine+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology100 enrolled2 locationsNCT04843982
Recruiting
Phase 4
Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia
SepsisDexamethasoneNeuroinflammatory Response+4 more
Radboud University Medical Center52 enrolled1 locationNCT06624436
Recruiting
Phase 4
Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Disease
PreventionAutoimmune DiseasesConnective Tissue Disease+2 more
Tongji Hospital800 enrolled1 locationNCT06499233
Completed
Phase 4
Relationship of serological levels for death receptors (TNFR1, TRAIL -R2, FAS ) With early pancreatic ß cell Apoptosis and Follow up after DPP4 inhibitors treatment in Syrian type 2 diabetic and impaired fasting glucose patients
the research problem is to study serum apoptotic biomarkers and inflammatory mediators in naive drug prediabetes to determine whether drug intervention (DPP4inhibitors ) can slow down or reverse apoptosis of pancreatic beta cell in order to limit conversion prediabetes to T2DM .
rama ayash -Damascus university ,-pharmacy college88 enrolled1 locationACTRN12624001135505
Recruiting
Phase 4
Subcutaneous Interval Lengthening of Vedolizumab for Economic Research
Inflammatory Bowel Diseases
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)40 enrolled1 locationNCT06584162
Recruiting
Phase 4
Subcutaneous Infliximab After A Previous Intravenous Dose Optimization
Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW275 enrolled15 locationsNCT06113913
Recruiting
Phase 4
Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock
SepsisSystemic Inflammatory Response SyndromeSeptic Shock+1 more
Kingman Regional Medical Center50 enrolled1 locationNCT06122987
Recruiting
Phase 4
Subcutaneous Immunoglobulin in De-novo CIDP (SIDEC)
CIDP - Chronic Inflammatory Demyelinating Polyneuropathy
University of Aarhus60 enrolled4 locationsNCT04589299
Recruiting
Phase 4
Control Crohn Safe Trial
Inflammatory Bowel DiseasesCrohn Disease
Maastricht University Medical Center158 enrolled6 locationsNCT03917303
Recruiting
Phase 4
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Non-small Cell Lung CancerOpioid UseAnesthesia+4 more
University of Crete70 enrolled1 locationNCT05172739
Not Yet Recruiting
Phase 4
A study comparing the effect of intravenous and oral iron supplementation on the quality of life of inflammatory bowel disease patients with iron deficiency without anaemia
Inflammatory Bowel DiseaseHypoferritinaemia
Dr Stephen Inns58 enrolled1 locationACTRN12617000586314
Completed
Phase 4
Impact of lung protective ventilatory strategy on systemic and pulmonary inflammatory responses during laparoscopic surgery: is it really helpful?
Inflammatory stress in patients undergoing laparoscopic gynaecological surgery
Afyon Kocatepe University40 enrolled1 locationACTRN12614000978662
Recruiting
Phase 3Phase 4
De novo combination allopurinol-thiopurine vs standard thiopurine in inflammatory bowel disease (IBD) patients escalating to immunomodulators: a randomized controlled trial
Inflammatory Bowel Disease
Eastern Health140 enrolled7 locationsACTRN12613001347752
Not Yet Recruiting
Phase 4
In children with inflammatory bowel disease and iron deficiency, does intravenous iron therapy with Ferric Carboxymaltose significantly improve cognitive function, quality of life and iron status.
Paediatric Inflammatory Bowel DiseaseIron deficiency without anaemiaIron deficiency anaemia
Gastroenterology Department, Royal Children's Hospital - Brisbane50 enrolled1 locationACTRN12613000751774
Completed
Phase 4
A prospective, multi-centre randomised comparative study of implant fit, clinical outcomes and satisfaction with the Stryker Accolade II Hip Stem compared to the Corail Hip Stem
Total Hip Replacement SurgeryNon-Inflammatory Degenerative Joint Disease of the Hip
Stryker Australia Pty Ltd250 enrolled1 locationACTRN12613000629730