Phase 1 Inhibitors Clinical Trials
7 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–7 of 7 trials
Recruiting
Phase 1
Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes II
Diabetes Mellitus, Type 2Type 2 DiabetesAspirin+2 more
Montreal Heart Institute30 enrolled1 locationNCT05702463
Recruiting
Phase 1
Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma
MelanomaNeoplasmsNeoplasms by Site+7 more
Yana Najjar50 enrolled2 locationsNCT04572451
Recruiting
Phase 1
Personalized mRNA Cancer Vaccine for Gastrointestinal Solid Tumor Treatment
Gastrointestinal TumorsPersonalized Neoantigen Vaccine in Combination With Anti-PD-1 Inhibitors in Standard Therapy-Failed and Adjuvant Therapy
Ruijin Hospital40 enrolled1 locationNCT07067385
Recruiting
Phase 1
Phase I Study of JYP0322 in ROS1 Fusion-Positive Solid Tumors
Lung NeoplasmsBrain NeoplasmsProtein Kinase Inhibitors+1 more
Guangzhou JOYO Pharma Co., Ltd101 enrolled1 locationNCT06128148
Recruiting
Phase 1
Phase I Study of MT1011 Injection in Healthy Subjects
Used in Patients Receiving Anticoagulant Therapy (e.g., Rivaroxaban or Apixaban, Inhibitors of Coagulation Factor Xa) Who Require Reversal of Anticoagulation
Shaanxi Micot Pharmaceutical Technology Co., Ltd.40 enrolled1 locationNCT07024160
Recruiting
Phase 1Phase 2
A Study of Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS Mutations
EGFR Tyrosine Kinase Inhibitors Plus Cyclin-dependent Kinase 4/6 Inhibitor
Sun Yat-sen University71 enrolled1 locationNCT06947811
Completed
Phase 1
Understanding the blood level of a new coagulant factor VIIa in participants with congenital Haemophilia A
Congenital Hemophilia A in subjects with or without Inhibitors to Factor VIII
LFB USA, Inc.28 enrolled3 locationsACTRN12620001152910