Phase 1 Initial Clinical Trials

3 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–3 of 3 trials

Recruiting

Phase 1

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Male and Female Subjects and Safety, Tolerability, Pharmacokinetics, and Pilot Efficacy Biomarkers in Subjects With Cold Agglutinin Disease

First in Man Study to Evaluate Initial Safety

Gliknik Inc.70 enrolled1 locationNCT05318534

Suspended

Phase 1

Bioavailability of orally administered gamma-glutamylcysteine

This bioavailability trial represents an initial investigation in healthy volunteers to determine the potential of gamma-glutamylcysteine (GGC) to augment cellular glutathione levels. Glutathione depletion is associated with numerous age related disorders.

University of New South Wales18 enrolled1 locationACTRN12612000952842

Completed

Phase 1

A randomised, double-blind, comparator study to assess the safety & tolerability of a single injection into the knee joint of MSB-CAR001 when combined with Hyaluronan compared to Hyaluronan alone in patients who have recently undergone an Anterior Cruciate Ligament Reconstruction.

Anterior Cruciate Ligament (ACL) reconstruction following an initial, unilateral acute ACL injury.Osteoarthritis post ACL repair

Mesoblast Ltd24 enrolled1 locationACTRN12609001018202