Phase 1 Injury Clinical Trials
55 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 55 trials
Recruiting
Phase 1Phase 2
Psilocybin to Treat Depression in Spinal Cord Injury
Depression - Major Depressive DisorderSpinal Cord InjuryVeteran
James J. Peters Veterans Affairs Medical Center30 enrolled1 locationNCT07251491
Recruiting
Phase 1Phase 2
Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation
Ischemia Reperfusion InjuryDelayed Graft Function
Rhode Island Hospital20 enrolled1 locationNCT04005469
Recruiting
Phase 1
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
ImpulsivitySuicidal IdeationMild Traumatic Brain Injury
VA Office of Research and Development55 enrolled1 locationNCT05647044
Recruiting
Phase 1Phase 2
Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage
Acute Kidney InjuryHIE
Medical College of Wisconsin30 enrolled1 locationNCT05853601
Recruiting
Phase 1
Evaluation of Lumitrace for Visualizing Ureters During Abdominopelvic Surgeries
Ureter Injury
MediBeacon10 enrolled1 locationNCT07080008
Recruiting
Phase 1Phase 2
CE-STAND: Cervical Epidural STimulation After Neurologic Damage
Spinal Cord Injury
University of Minnesota36 enrolled1 locationNCT06410001
Recruiting
Phase 1
Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury
Spinal Cord InjurySpasticityShockwave Therapy
Kessler Foundation12 enrolled1 locationNCT07501429
Recruiting
Phase 1
Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury
Spinal Cord Injury
HealthPartners Institute12 enrolled1 locationNCT07384052
Recruiting
Phase 1Phase 2
NVG-291 in Spinal Cord Injury Subjects
chronic spinal cord injurySpinal Cord InjuriesSubacute Spinal Cord Injury
NervGen Pharma40 enrolled1 locationNCT05965700
Recruiting
Phase 1Phase 2
Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury
Acute Kidney Injury
Hope Biosciences LLC70 enrolled3 locationsNCT06654193
Recruiting
Phase 1
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
Spinal Cord InjurySpinal Cord Injury CervicalSpinal Cord Injury, Chronic+2 more
Lineage Cell Therapeutics, Inc.10 enrolled2 locationsNCT06841770
Recruiting
Phase 1Phase 2
Low-Tech Treatments for Obstructive Sleep Apnea
Traumatic Brain Injury (TBI)Obstructive Sleep Apnea (OSA)
Uniformed Services University of the Health Sciences60 enrolled1 locationNCT07301710
Recruiting
Phase 1
Spinal Cord Injury Neuroprotection With Glyburide
Acute Spinal Cord Injury
Francis Farhadi12 enrolled1 locationNCT05426681
Recruiting
Phase 1
Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial
EfficacySafetySpinal Cord Injury+4 more
XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.12 enrolled1 locationNCT06976229
Recruiting
Phase 1Phase 2
Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
Spinal Cord Injury
Glen Foster10 enrolled2 locationsNCT06691165
Recruiting
Phase 1
Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function
Peripheral nerve injury
Vanderbilt University Medical Center18 enrolled1 locationNCT02359825
Recruiting
Phase 1
Clinical Assessment of Protopic® Ointment in Deep Partial-Thickness Burns
Burn Injury
Vanderbilt University Medical Center18 enrolled1 locationNCT05856994
Recruiting
Phase 1
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
Mild Traumatic Brain InjuryHeadacheBrain Concussion+1 more
State University of New York - Upstate Medical University60 enrolled1 locationNCT06112093
Recruiting
Phase 1Phase 2
MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction
PostpartumPreeclampsiaCell Therapy+2 more
Universitas Padjadjaran80 enrolled1 locationNCT07183384
Recruiting
Phase 1Phase 2
Phase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord Injury
Acute Spinal Cord Injury (SCI)
Technophage, SA28 enrolled2 locationsNCT06677229