Phase 1 Injury Clinical Trials
58 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 58 trials
Recruiting
Phase 1Phase 2
Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury
SepsisAcute Kidney Injury
Centre Hospitalier Universitaire de Nīmes14 enrolled2 locationsNCT07236463
Recruiting
Phase 1
Akkermansia Muciniphila (AKK) for Radiation-Induced Skin Injury
Radiation-Induced Skin Injury
West China Hospital40 enrolled2 locationsNCT07635277
Recruiting
Phase 1
Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures
Male Urogenital DiseasesUrologic DiseasesUrethral Stricture+1 more
Wake Forest University Health Sciences10 enrolled2 locationsNCT03258658
Recruiting
Phase 1Phase 2
Double Dose 4-AP on Functional Recovery After Spinal Cord Injury
SCI - Spinal Cord Injury
Shirley Ryan AbilityLab27 enrolled1 locationNCT06853015
Recruiting
Phase 1
FES Cycling With BFR in the Spinal Cord Injury Population
Spinal Cord InjuryMetabolic Diseases, Type 2 Diabetes, Cardiovascular DiseaseCardio Vascular Disease
Dr. B. Catharine. Craven6 enrolled1 locationNCT07588503
Recruiting
Phase 1Phase 2
Psilocybin to Treat Depression in Spinal Cord Injury
Depression - Major Depressive DisorderSpinal Cord InjuryVeteran
James J. Peters Veterans Affairs Medical Center30 enrolled1 locationNCT07251491
Recruiting
Phase 1Phase 2
Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation
Ischemia Reperfusion InjuryDelayed Graft Function
Rhode Island Hospital20 enrolled1 locationNCT04005469
Recruiting
Phase 1
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
ImpulsivitySuicidal IdeationMild Traumatic Brain Injury
VA Office of Research and Development55 enrolled1 locationNCT05647044
Recruiting
Phase 1Phase 2
Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage
Acute Kidney InjuryHIE
Medical College of Wisconsin30 enrolled1 locationNCT05853601
Recruiting
Phase 1
Evaluation of Lumitrace for Visualizing Ureters During Abdominopelvic Surgeries
Ureter Injury
MediBeacon10 enrolled1 locationNCT07080008
Recruiting
Phase 1Phase 2
CE-STAND: Cervical Epidural STimulation After Neurologic Damage
Spinal Cord Injury
University of Minnesota36 enrolled1 locationNCT06410001
Recruiting
Phase 1
Shockwave for Elbow and Wrist Spasticity in People With Spinal Cord Injury
Spinal Cord InjurySpasticityShockwave Therapy
Kessler Foundation12 enrolled1 locationNCT07501429
Recruiting
Phase 1
Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury
Spinal Cord Injury
HealthPartners Institute12 enrolled1 locationNCT07384052
Recruiting
Phase 1Phase 2
NVG-291 in Spinal Cord Injury Subjects
chronic spinal cord injurySpinal Cord InjuriesSubacute Spinal Cord Injury
NervGen Pharma40 enrolled1 locationNCT05965700
Recruiting
Phase 1Phase 2
Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury
Acute Kidney Injury
Hope Biosciences LLC70 enrolled3 locationsNCT06654193
Recruiting
Phase 1
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
Spinal Cord InjurySpinal Cord Injury CervicalSpinal Cord Injury, Chronic+2 more
Lineage Cell Therapeutics, Inc.10 enrolled2 locationsNCT06841770
Recruiting
Phase 1Phase 2
Low-Tech Treatments for Obstructive Sleep Apnea
Traumatic Brain Injury (TBI)Obstructive Sleep Apnea (OSA)
Uniformed Services University of the Health Sciences60 enrolled1 locationNCT07301710
Recruiting
Phase 1
Spinal Cord Injury Neuroprotection With Glyburide
Acute Spinal Cord Injury
Francis Farhadi12 enrolled1 locationNCT05426681
Recruiting
Phase 1
Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial
EfficacySafetySpinal Cord Injury+4 more
XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.12 enrolled1 locationNCT06976229
Recruiting
Phase 1Phase 2
Improving 24-hour Blood Pressure Stability in Spinal Cord Injury With Low Oxygen Therapy
Spinal Cord Injury
Glen Foster10 enrolled2 locationsNCT06691165