Phase 3 Injury Clinical Trials
66 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 66 trials
Recruiting
Phase 3
Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial
SurgeryChronic Kidney DiseasesAcute Kidney Injury+1 more
Hamilton Health Sciences Corporation100 enrolled3 locationsNCT06337838
Recruiting
Phase 3
Efficacy of Early Continuous Infusion of HSS on the Neurological Outcome at 6 Months in TBI Patients.
TBI (Traumatic Brain Injury)
Nantes University Hospital760 enrolled23 locationsNCT07319208
Recruiting
Phase 2Phase 3
Pirfenidone Capsules in the Treatment of Radiation-induced Lung Injury With or Without Immune Pneumonia
Radiation Induced Lung InjuryImmune-related Pneumonia
Beijing Continent Pharmaceutical Co, Ltd.298 enrolled36 locationsNCT07388680
Recruiting
Phase 3
This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.
Peripheral Nerve Injury Upper LimbPeripheral Nerve Injury (PNI)
Neuraptive Therapeutics Inc.98 enrolled12 locationsNCT06616025
Recruiting
Phase 3
Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT
Acute Kidney Injury (AKI)Regional Citrate Anticoagulation (RCA)Continuous Renal Replacement Therapy (CRRT)
Vantive Health LLC40 enrolled14 locationsNCT05399537
Recruiting
Phase 3
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)
Mild Traumatic Brain InjuryAdult Growth Hormone Deficiency
VA Office of Research and Development172 enrolled4 locationsNCT04867317
Recruiting
Phase 3
Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children
Musculoskeletal injuryPediatricsSprain and Strain of Ankle+2 more
University of Calgary60 enrolled2 locationsNCT07145645
Recruiting
Phase 3
Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine
Limb Injury
Assistance Publique - Hôpitaux de Paris300 enrolled5 locationsNCT06464146
Recruiting
Phase 3
Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults
Traumatic Brain Injury
London School of Hygiene and Tropical Medicine5,000 enrolled2 locationsNCT04521881
Recruiting
Phase 3
Prehospital Analgesia INtervention Trial (PAIN)
Traumatic Injury
Jason Sperry994 enrolled11 locationsNCT05437575
Recruiting
Phase 3
Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases
Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817
Recruiting
Phase 2Phase 3
Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery
Injury of Ureter During Surgery (Disorder)
Curadel Surgical Innovations, Inc.336 enrolled10 locationsNCT06101745
Recruiting
Phase 3
Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children
Trauma InjuryHemorrhagic Shock
Philip Spinella1,000 enrolled23 locationsNCT06070350
Recruiting
Phase 2Phase 3
Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients
Acute Kidney Injury
The University of Texas Health Science Center, Houston100 enrolled1 locationNCT06531642
Recruiting
Phase 3
PRophylaxis Against Early VENTilator-associated Infections in Acute Brain Injury
Intensive Care MedicineAcute brain injuryQuality of Life+4 more
The George Institute3,300 enrolled9 locationsNCT06819592
Recruiting
Phase 2Phase 3
FFP In Traumatic BRAin INjury (FIT-BRAIN) Trial
Moderate to severe traumatic brain injury
Northwestern University357 enrolled1 locationNCT06062888
Recruiting
Phase 3
Low-dose Arginine-vasopressin Supplementation on Post-transplant Acute Kidney Injury After Liver Transplantation (AVENIR Trial)
Acute Kidney Injury Post Liver Transplantation
Assistance Publique - Hôpitaux de Paris304 enrolled1 locationNCT06344442
Recruiting
Phase 3
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 2Phase 3
Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support
Liver InjuryCholine Deficiency
Protara Therapeutics129 enrolled14 locationsNCT06910943
Recruiting
Phase 2Phase 3
A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation
Acute Respiratory Distress Syndrome (ARDS)Acute Lung Injury(ALI)Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome
Shanghai University of Traditional Chinese Medicine60 enrolled1 locationNCT07342205